The porcine model has contributed significantly to biomedical research over many decades.
The similar size and anatomy of pig and human organs make this model particularly …

This book describes the new imaging techniques being developed to monitor physiological,
cellular and subcellular function within living animals. This exciting field of imaging science …

Fundamentally important to the future of pulmonary medicine is a better description and
understanding of the human lung and its response to disease, injury, and treatment, which is …

X-ray computed tomography is a reliable technique for the detection and longitudinal
monitoring of pulmonary nodules. In preclinical stages of diagnostic or therapeutic …

The lung is comprised of more than 40 distinct cell types that support a complex 3-
dimensional (3D) architecture that is required for efficient lung function. Loss of this proper …

The interactions between immune cells and epithelial cells influence the progression of
many respiratory diseases, such as chronic obstructive pulmonary disease (COPD). In vitro …

Precision-cut lung slices (PCLS) represent an ex vivo model widely used in visualizing
interactions between lung structure and function. The major advantage of this technique is …

The ability to visualize molecular processes and cellular regulators of complex pulmonary
diseases such as asthma, chronic obstructive pulmonary disease (COPD), or adult …

The respiratory system, including the peripheral lungs, large airways and trachea, is one of
the most recently evolved adaptations to terrestrial life. To support the exchange of …

In the nineteenth century, there was a dispute about the existence of a lung alveolar
epithelium which remained unsolved until the invention of electron microscopy (EM) and its …