Structural and functional changes of pulmonary circulation related to pathophysiology of
pulmonary arterial hypertension (PAH) remain to be fully elucidated. Angiographic …

Acute and chronic lung diseases are almost invariably associated with some degree of
inflammation. Cells that evolved as an effective mechanism to counter infection and heal …

Non-invasive micro-CT imaging techniques have been developed to investigate lung
structure in free-breathing rodents. In this study, we investigate the utility of retrospectively …

Although proinflammatory cell signaling in the alveolo-capillary region predisposes to acute
lung injury, key cell-signaling mechanisms remain inadequately understood. Alveolo …

The technical advances in microscopy imaging techniques have been applied to assess the
fate of drugs for researching respiratory drug delivery in ex vivo and in vivo experiments …

In whole adult mouse lung, full identification of airway nerves (or other cellular/subcellular
objects) has not been possible due to patchy distribution and micron-scale size. Here we …

Confocal endomicroscopes aim at providing to the clinician microscopic imaging of a living
tissue. The currently available microendoscopic devices use the principle of confocal …

As the lung is constantly exposed to both innocuous and potentially noxious antigens, a
thorough understanding of both innate and adaptive immune responses in this organ is of …

During the last decades, the study of cell behavior was largely accomplished in uncoated or
extracellular matrix (ECM)-coated plastic dishes. To date, considerable cell biological efforts …

During the last 10+ years biologically and clinically significant questions about postnatal
lung development could be answered due to the application of modern cutting-edge …