Objective The mechanisms by which bariatric surgeries so effectively and lastingly reduce
body weight and normalize metabolic dysfunction are not well understood. Fibroblast growth …

Objective: Bariatric surgery can profoundly improve glucose and lipid metabolism in diabetic
rats. Fibroblast growth factor 21 (FGF21) is an important hormone with multiple metabolic …

Background Fibroblast growth factor 21 (FGF21) is elevated in obesity. Objectives We
investigated the circulating level of FGF21 and the expression of FGF21, beta-klotho (KLB) …

Background: Bariatric surgery is a popular and effective therapeutic intervention for obesity,
which is an abnormal health condition that is prevalent worldwide. Metabolic improvements …

Bariatric surgery procedures, such as Roux-en-Y gastric bypass (RYGB) and vertical sleeve
gastrectomy (VSG), are the most effective interventions available for sustained weight loss …

Context Fibroblast growth factor (FGF) 19 and FGF21 are secreted by the intestine and liver
in response to macronutrient intake. Intestinal resection and reconstruction via bariatric …

Bariatric surgery has proven to be the most effective treatment for controlling hyperglycemia
in severely obese patients with diabetes. We show that fibroblast growth factor 19 (FGF19), a …

Background & aims Fibroblast growth factor 19 (FGF19) and 21 (FGF21) have emerged as
key regulators of energy homeostasis. Our aim was to analyze the impact of weight loss …

OBJECTIVE Roux-en-Y gastric bypass (RYGB) in humans can remit type 2 diabetes, but the
operative mechanism is not completely understood. In mice, fibroblast growth factor (FGF) …

The homeostatic systems regulating energy and glucose metabolism perform a complex
balancing act of meeting short term requirements for increased energy whilst maintaining …