The longer term outcome of children born to mothers with epilepsy

N Adab, U Kini, J Vinten, J Ayres, G Baker… - Journal of Neurology …, 2004 - jnnp.bmj.com
Objectives: To determine the prevalence of cognitive delay and possible associated
dysmorphic features in children exposed to antiepileptic drugs (AEDs) in utero. Design …

Additional educational needs in children born to mothers with epilepsy

N Adab, A Jacoby, D Smith… - Journal of Neurology …, 2001 - jnnp.bmj.com
OBJECTIVES To examine the relative risks of additional educational needs (AENs) in
children exposed to antiepileptic drug (AED) monotherapy and polytherapy regimes in utero …

Epilepsy and pregnancy: report of an Epilepsy Research Foundation Workshop

C Barrett, A Richens - Epilepsy research, 2003 - Elsevier
Pregnancy in women with epilepsy (WWE) is known to be associated with a higher risk of
congenital malformations than is associated with pregnancy in non-epileptic women …

IQ at 6 years after in utero exposure to antiepileptic drugs: a controlled cohort study

GA Baker, RL Bromley, M Briggs, CP Cheyne… - Neurology, 2015 - AAN Enterprises
Objective: To delineate the risk to child IQ associated with frequently prescribed antiepileptic
drugs. Methods: Children born to women with epilepsy (n= 243) and women without …

The prevalence of neurodevelopmental disorders in children prenatally exposed to antiepileptic drugs

RL Bromley, GE Mawer, M Briggs, C Cheyne… - Journal of Neurology …, 2013 - jnnp.bmj.com
The aim of this study was to compare the prevalence of diagnosed neurodevelopmental
disorders in children exposed, in utero, to different antiepileptic drug treatments. A …

Neuropsychological effects of exposure to anticonvulsant medication in utero

J Vinten, N Adab, U Kini, J Gorry, J Gregg, GA Baker - Neurology, 2005 - AAN Enterprises
Objective: To investigate the long-term differential drug effects on cognitive functioning in
school-aged children exposed to antiepileptic drugs (AEDs) in utero. Methods: Mothers with …

Children exposed to valproate in utero—population based evaluation of risks and confounding factors for long-term neurocognitive development

K Eriksson, K Viinikainen, A Mönkkönen, M Äikiä… - Epilepsy research, 2005 - Elsevier
PURPOSE:: To evaluate neurological and cognitive functioning of school-aged (≥ 6 years)
children exposed to valproate monotherapy in utero in a population based, evaluator …

Association of prenatal exposure to valproate and other antiepileptic drugs with intellectual disability and delayed childhood milestones

CA Daugaard, L Pedersen, Y Sun, JW Dreier… - JAMA network …, 2020 - jamanetwork.com
Importance There is concern about neurodevelopmental outcomes associated with prenatal
exposure to valproate and other antiepileptic drugs (AEDs) among children of mothers with …

Critical relationship between sodium valproate dose and human teratogenicity: results of the Australian register of anti-epileptic drugs in pregnancy

FJ Vajda, TJ O'brien, A Hitchcock, J Graham… - Journal of Clinical …, 2004 - Elsevier
To compare the incidence of foetal malformations (FMs) in pregnant women with epilepsy
treated with different anti-epileptic drugs (AED) and doses, and the influence of seizures …

Cognitive function at 3 years of age after fetal exposure to antiepileptic drugs

KJ Meador, GA Baker, N Browning… - New England journal …, 2009 - Mass Medical Soc
Background Fetal exposure of animals to antiepileptic drugs at doses lower than those
required to produce congenital malformations can produce cognitive and behavioral …