The longer term outcome of children born to mothers with epilepsy
Objectives: To determine the prevalence of cognitive delay and possible associated
dysmorphic features in children exposed to antiepileptic drugs (AEDs) in utero. Design …
dysmorphic features in children exposed to antiepileptic drugs (AEDs) in utero. Design …
Additional educational needs in children born to mothers with epilepsy
N Adab, A Jacoby, D Smith… - Journal of Neurology …, 2001 - jnnp.bmj.com
OBJECTIVES To examine the relative risks of additional educational needs (AENs) in
children exposed to antiepileptic drug (AED) monotherapy and polytherapy regimes in utero …
children exposed to antiepileptic drug (AED) monotherapy and polytherapy regimes in utero …
Epilepsy and pregnancy: report of an Epilepsy Research Foundation Workshop
C Barrett, A Richens - Epilepsy research, 2003 - Elsevier
Pregnancy in women with epilepsy (WWE) is known to be associated with a higher risk of
congenital malformations than is associated with pregnancy in non-epileptic women …
congenital malformations than is associated with pregnancy in non-epileptic women …
IQ at 6 years after in utero exposure to antiepileptic drugs: a controlled cohort study
Objective: To delineate the risk to child IQ associated with frequently prescribed antiepileptic
drugs. Methods: Children born to women with epilepsy (n= 243) and women without …
drugs. Methods: Children born to women with epilepsy (n= 243) and women without …
The prevalence of neurodevelopmental disorders in children prenatally exposed to antiepileptic drugs
RL Bromley, GE Mawer, M Briggs, C Cheyne… - Journal of Neurology …, 2013 - jnnp.bmj.com
The aim of this study was to compare the prevalence of diagnosed neurodevelopmental
disorders in children exposed, in utero, to different antiepileptic drug treatments. A …
disorders in children exposed, in utero, to different antiepileptic drug treatments. A …
Neuropsychological effects of exposure to anticonvulsant medication in utero
Objective: To investigate the long-term differential drug effects on cognitive functioning in
school-aged children exposed to antiepileptic drugs (AEDs) in utero. Methods: Mothers with …
school-aged children exposed to antiepileptic drugs (AEDs) in utero. Methods: Mothers with …
Children exposed to valproate in utero—population based evaluation of risks and confounding factors for long-term neurocognitive development
K Eriksson, K Viinikainen, A Mönkkönen, M Äikiä… - Epilepsy research, 2005 - Elsevier
PURPOSE:: To evaluate neurological and cognitive functioning of school-aged (≥ 6 years)
children exposed to valproate monotherapy in utero in a population based, evaluator …
children exposed to valproate monotherapy in utero in a population based, evaluator …
Association of prenatal exposure to valproate and other antiepileptic drugs with intellectual disability and delayed childhood milestones
CA Daugaard, L Pedersen, Y Sun, JW Dreier… - JAMA network …, 2020 - jamanetwork.com
Importance There is concern about neurodevelopmental outcomes associated with prenatal
exposure to valproate and other antiepileptic drugs (AEDs) among children of mothers with …
exposure to valproate and other antiepileptic drugs (AEDs) among children of mothers with …
Critical relationship between sodium valproate dose and human teratogenicity: results of the Australian register of anti-epileptic drugs in pregnancy
FJ Vajda, TJ O'brien, A Hitchcock, J Graham… - Journal of Clinical …, 2004 - Elsevier
To compare the incidence of foetal malformations (FMs) in pregnant women with epilepsy
treated with different anti-epileptic drugs (AED) and doses, and the influence of seizures …
treated with different anti-epileptic drugs (AED) and doses, and the influence of seizures …
Cognitive function at 3 years of age after fetal exposure to antiepileptic drugs
Background Fetal exposure of animals to antiepileptic drugs at doses lower than those
required to produce congenital malformations can produce cognitive and behavioral …
required to produce congenital malformations can produce cognitive and behavioral …