We investigated the association between genetic polymorphisms of IL17A, TLR4 and
P2RX7 genes and chronic obstructive pulmonary disease (COPD) in a Han population. We …

Chronic inflammation is a hallmark of pulmonary diseases, which leads to lung parenchyma
destruction (emphysema) and obstructive bronchiolitis occurring in both chronic obstructive …

Background Genetic variants of dipeptidyl peptidase 10 (DPP10) have been suggested to
contribute to the development of NSAID‐exacerbated respiratory disease (NERD). However …

Molecular pathology of chronic obstructive pulmonary disease (COPD) is still being
investigated to discover relationships with disease pathogenesis. Evidence of plasminogen …

It is well known that cigarette smoking is the major risk factor for chronic obstructive
pulmonary disease (COPD). However, only 10%–20% of chronic heavy cigarette smokers …

Rationale: Chronic obstructive pulmonary disease (COPD) is a complex disorder with high
mortality worldwide. Studies on the role of candidate genes and their polymorphisms in …

Chronic obstructive pulmonary disease (COPD) is a major health problem. The disease is
driven by abnormal inflammatory reactions in response to inhaled particles and fumes …

Proteinase/antiproteinase imbalance is recognized to play an important role in the
pathogenesis of chronic obstructive pulmonary disease (COPD). A relative increase in the …

Rationale: Chronic obstructive pulmonary disease (COPD) is a complex disease influenced
by multiple genes and environmental factors. A region on chromosome 2q has been shown …

The purpose of this study was to investigate the possible roles of the cytokines genes in the
development of chronic obstructive pulmonary disease (COPD). Polymorphisms in the …