Ethanol and nicotine are the most abused drugs, and it is well known that co-abuse of
ethanol and nicotine is frequent in human beings. We have previously obtained results …

Ethanol shares with all major dependence producing drugs the ability to activate brain
mesocorticolimbic dopamine neurons, an important part of the brain reward systems. This …

Aims: Concurrent use of ethanol and nicotine (tobacco) is often seen in human beings. In
previous animal experiments, we have demonstrated that nicotinic acetylcholine receptors …

It has been suggested that the mesolimbic dopamine activating and the reinforcing
properties of ethanol involve activation of central nicotinic acetylcholine receptors. To test …

The most commonly abused drugs, alcohol and nicotine, are likely also the most costly
drugs in terms of health and societal costs. A large body of evidence from epidemiological …

Alcohol and nicotine are commonly abused drugs in humans and evidence suggests that
neuronal nicotinic acetylcholine receptors (nAChRs) in the midbrain dopamine system are …

Ethanol and nicotine have many psychopharmacological effects in common, which could
explain why coadministration of these compounds often is observed in individuals. In the …

Ethanol-induced elevations of accumbal dopamine levels have been linked to the
reinforcing properties of the drug. However, it has not yet been demonstrated where the …

Rationale and objectives The sensitivity to ethanol central effects is partially determined by
the subunit composition of brain nicotinic acetylcholine receptors (nAChRs). Thus, the …

It has been suggested that ethanol exerts its mesolimbic dopamine activating effects and its
reinforcing effects via interaction with central nicotinic acetylcholine receptors, thus providing …