Tuberculosis is still a major health problem in the world. Initial interactions between
Mycobacterium tuberculosis and the host mark the pathway of infection and the subsequent …

Mycobacterium tuberculosis is a highly efficient pathogen, killing millions of infected people
annually. The capacity of M. tuberculosis to survive and cause disease is strongly correlated …

A major challenge in tuberculosis (TB) is to improve current vaccination and therapeutic
strategies and this requires a fine understanding of the mechanisms that mediate protection …

Mycobacterium tuberculosis, the causative agent of tuberculosis, has infected humans for
millennia. M. tuberculosis is well adapted to establish infection, persist in the face of the host …

Following infection with Mycobacterium tuberculosis, the causative agent of tuberculosis
(TB), most human hosts are able to contain the infection and avoid progression to active TB …

Tuberculosis (TB) is the outcome of an insidious, protracted infection with Mycobacterium
tuberculosis (Mtb). It primarily affects the lung and is characterized by extensive focal …

The ability of Mycobacterium tuberculosis to cause disease hinges upon successfully
thwarting the innate defenses of the macrophage host cell. The pathogen's trump card is its …

In this review, we discuss the 'knowns' and 'unknowns' of host defence towards
Mycobacterium tuberculosis. With regard to the 'knowns', both protective and …

Mycobacterium tuberculosis, the etiological agent of tuberculosis (TB), is an extremely
successful pathogen that adapts to survive within the host. During the latency phase of …

Highlights•TB is a nonresolving inflammatory disease.•Inflammatory mediators are
intertwined in networks during TB.•The pattern of infected cell death affects inflammation in …