[HTML][HTML] The combined effects of physicochemical properties of size-fractionated ambient particulate matter on in vitro toxicity in human A549 lung epithelial cells

US Akhtar, N Rastogi, RD McWhinney, B Urch… - Toxicology Reports, 2014 - Elsevier
Epidemiological and toxicological studies have suggested that the health effects associated
with exposure to particulate matter (PM) are related to the different physicochemical …

Exposure to ambient concentrations of particulate air pollution does not influence vascular function or inflammatory pathways in young healthy individuals

EV Bräuner, P Møller, L Barregard, LO Dragsted… - Particle and Fibre …, 2008 - Springer
Background Particulate air pollution is associated with increased risk of cardiovascular
events although the involved mechanisms are poorly understood. The objective of the …

Particle induced toxicity in relation to transition metal and polycyclic aromatic hydrocarbon contents

ME Gerlofs-Nijland, M Rummelhard… - … science & technology, 2009 - ACS Publications
Exposure to ambient particulate matter (PM) is statistically significantly associated with
morbidity and mortality. The objectives of this study were (a) to investigate in vivo pulmonary …

Review of acellular assays of ambient particulate matter oxidative potential: methods and relationships with composition, sources, and health effects

JT Bates, T Fang, V Verma, L Zeng… - … science & technology, 2019 - ACS Publications
Oxidative stress is a potential mechanism of action for particulate matter (PM) toxicity and
can occur when the body's antioxidant capacity cannot counteract or detoxify harmful effects …

Epidemiology of fine particulate air pollution and human health: biologic mechanisms and who's at risk?

CA Pope 3rd - Environmental health perspectives, 2000 - ehp.niehs.nih.gov
This article briefly summarizes the epidemiology of the health effects of fine particulate air
pollution, provides an early, somewhat speculative, discussion of the contribution of …

Oxidative stress and inflammation generated DNA damage by exposure to air pollution particles

P Møller, PH Danielsen, DG Karottki, K Jantzen… - … research/Reviews in …, 2014 - Elsevier
Generation of oxidatively damaged DNA by particulate matter (PM) is hypothesized to occur
via production of reactive oxygen species (ROS) and inflammation. We investigated this …

Oxidative potential versus biological effects: a review on the relevance of cell-free/abiotic assays as predictors of toxicity from airborne particulate matter

J Øvrevik - International journal of molecular sciences, 2019 - mdpi.com
Background and Objectives: The oxidative potential (OP) of particulate matter (PM) in cell-
free/abiotic systems have been suggested as a possible measure of their biological …

Respiratory health effects of airborne particulate matter: the role of particle size, composition, and oxidative potential—the RAPTES project

M Strak, NAH Janssen, KJ Godri… - Environmental …, 2012 - ehp.niehs.nih.gov
Background: Specific characteristics of particulate matter (PM) responsible for associations
with respiratory health observed in epidemiological studies are not well established. High …

Recent Insights into Particulate Matter (PM2.5)-Mediated Toxicity in Humans: An Overview

P Thangavel, D Park, YC Lee - International journal of environmental …, 2022 - mdpi.com
Several epidemiologic and toxicological studies have commonly viewed ambient fine
particulate matter (PM2. 5), defined as particles having an aerodynamic diameter of less …

Global perspective on the oxidative potential of airborne particulate matter: a synthesis of research findings

A Saffari, N Daher, MM Shafer… - … science & technology, 2014 - ACS Publications
An emerging hypothesis in the field of air pollution is that oxidative stress is one of the
important pathways leading to adverse health effects of airborne particulate matter (PM). To …