Abstract Introduction: Matrix metalloproteinases (MMPs) are classified in the family of zinc-
dependent endopeptidases, which can degrade various components of an extracellular …

Background: Cancer is a wide range cellular level disease that occurs when cells go
through uncontrolled division and growth. The mechanisms by which the cells undergo …

Matrix metalloproteinases (MMPs), also designated as matrixins, play a central role in many
biological processes and are involved both in physiologic cellular processes and in …

The important role of matrix metalloproteinases (MMPs) in the process of carcinogenesis is
well established. However, despite very promising activity in a plethora of preclinical …

Cutting-edge investigators review the current status of the entire field, from the biology of
MMPs through the current clinical studies. The authors include many leading scientists from …

Introduction: The overexpression of matrix metalloproteinase (MMP) plays an important role
in the context of tumor invasion and metastasis, and MMP-2 has been characterized as the …

Matrix metalloproteinases (MMPs) consist of a multigene family of zinc‐dependent
extracellular matrix (ECM) remodeling endopeptidases implicated in pathological …

Inhibition of matrix metalloproteinases (MMPs), a family of proteolytic enzymes linked to
many aspects of cancer progression, has been explored as a therapeutic goal for almost two …

The matrix metalloproteinases (MMP) are a family of proteolytic enzymes that degrade
multiple components of the extracellular matrix. A large body of experimental and clinical …

Matrix metalloproteinases (MMPs) are identifiable members of proteolytic enzymes that can
degrade a wide range of proteins in the extracellular matrix (ECM). MMPs can be …