Affective disturbances during withdrawal from chronic intermittent ethanol inhalation in C57BL/6J and DBA/2J male mice

H Sidhu, M Kreifeldt, C Contet - Alcoholism: Clinical and …, 2018 - Wiley Online Library
Background Alcohol use disorders are characterized by a complex behavioral
symptomatology, which includes the loss of control over alcohol consumption and the …

Anxiety‐like behavior in mice in two apparatuses during withdrawal from chronic ethanol vapor inhalation

CL Kliethermes, K Cronise… - Alcoholism: Clinical and …, 2004 - Wiley Online Library
Background: Anxiety during ethanol withdrawal may be a factor in relapse to alcohol abuse
and dependence. Animal models of ethanol withdrawal have typically used forced …

Home cage activity and ingestive behaviors in mice following chronic ethanol vapor inhalation

CL Kliethermes, K Cronise, JC Crabbe - Physiology & behavior, 2005 - Elsevier
Although drug withdrawal may induce an anxiety-like state, decreased locomotion in tests of
anxiety-like behavior is an almost universal finding in rodent studies of ethanol withdrawal …

Assessing negative affect in mice during abstinence from alcohol drinking: Limitations and future challenges

S Bloch, KM Holleran, TL Kash, EM Vazey, JA Rinker… - Alcohol, 2022 - Elsevier
Alcohol use disorder (AUD) is frequently comorbid with mood disorders, and these co-
occurring neuropsychiatric disorders contribute to the development and maintenance of …

Withdrawal severity after chronic intermittent ethanol in inbred mouse strains

P Metten, ML Sorensen, AJ Cameron… - Alcoholism: Clinical …, 2010 - Wiley Online Library
Background: To study withdrawal, ethanol is usually administered chronically without
interruption. However, interest has recurred in models of episodic exposure. Increasing …

Chronic intermittent ethanol exposure produces persistent anxiety in adolescent and adult rats

CE Van Skike, JL Diaz‐Granados… - Alcoholism: clinical …, 2015 - Wiley Online Library
Background Ethanol (EtOH) dependence and tolerance in the adult are marked by
increased function of NMDA receptors and decreased function of GABAA receptors, which …

Assessment of affective and somatic signs of ethanol withdrawal in C57BL/6J mice using a short-term ethanol treatment

EE Perez, M De Biasi - Alcohol, 2015 - Elsevier
Alcohol is one of the most prevalent addictive substances in the world. Withdrawal
symptoms result from abrupt cessation of alcohol consumption in habitual drinkers. The …

Assessment of depression-like behavior and anhedonia after repeated cycles of binge-like ethanol drinking in male C57BL/6J mice

JJ Olney, SA Marshall, TE Thiele - Pharmacology Biochemistry and …, 2018 - Elsevier
Psychological depression is frequently linked to alcohol abuse and even serves as key
indicators of an alcohol use disorder (AUD). This relationship is supported by preclinical …

Chronic ethanol exposure increases voluntary home cage intake in adult male, but not female, Long–Evans rats

M Morales, MM McGinnis, BA McCool - Pharmacology Biochemistry and …, 2015 - Elsevier
The current experiment examined the effects of 10 days of chronic intermittent ethanol (CIE)
exposure on anxiety-like behavior and home cage ethanol intake using a 20% intermittent …

Sex differences in the behavioral sequelae of chronic ethanol exposure

NJ Jury, JF DiBerto, TL Kash, A Holmes - Alcohol, 2017 - Elsevier
Rates of alcohol use disorders (AUDs) differ between men and women, and there is also
marked variation between sexes in the effects of acute and chronic alcohol. In parallel to …