Puerarin extracted from Radix puerariae is well-known for its anti-oxidative and
neuroprotective activities. In this study, we investigated the protective effect of puerarin on …

Epidemiological data have indicated that estrogen replacement therapy (ERT) can decrease
the risk of developing Alzheimer's disease (AD). Phytoestrogens have been proposed as …

Puerarin (CAS Number 3681-99-0), a major isoflavone glycoside purified from Pueraria
lobata, was reported to posses antioxidative and estrogen-like biological activities. Recent …

Puerarin is a major isoflavone glycoside from the root of Pueraria lobata. It has been
reported that puerarin can protect neurons from oxidative stress-induced apoptosis …

Abstract β‐Amyloid protein (Aβ), a major protein component of brain senile plaques in
Alzheimer's disease, is known to be directly responsible for the production of reactive …

Elevated levels of β-amyloid (Aβ) in the brains being a hallmark of Alzheimer's disease have
been believed to play a critical role in the cognitive dysfunction that occurs in Alzheimer's …

Tumor necrosis factor-α (TNF-α), a potential proinflammatory cytokine, is an important
component involved in neuronal apoptosis associated with neuroinflammation in the central …

Puerarin extracted from Radix puerariae has been shown to exert neuroprotective effects.
However, it is still not known whether puerarin protects hippocampal neurons against cell …

Neurological diseases impose a tremendous and increasing burden on global health, and
there is currently no curative agent. Puerarin, a natural isoflavone extracted from the dried …

Puerarin suppresses autophagy to alleviate cerebral ischemia/reperfusion injury, and
accumulating evidence indicates that the AMPK-mTOR signaling pathway regulates the …