During the course of pancreatic neuroendocrine tumors (NETs), they generally become
more heterogeneous with individual cells exhibiting distinct molecular fingerprints. This …

Pancreatic neuroendocrine tumors (PNETs) are classified based on their histologic
differentiation and proliferative indices, which have been used extensively to determine …

Background: Data on inter-tumoral heterogeneity and clonal evolution of pancreatic
neuroendocrine neoplasms (panNENs) with liver metastasis are limited. The aim of this …

Aims: Using Single-cell RNA sequencing (scRNA-seq), we explored the spatiotemporal
heterogeneity of pancreatic neuroendocrine tumors (pNETs) and the underlying mechanism …

Recent data suggest that Pancreatic Neuroendocrine Tumours (PanNETs) originate from α-
or β-cells of the islets of Langerhans. The majority of PanNETs are non-functional and do not …

Neuroendocrine neoplasms (NENs) are a relatively rare group of heterogeneous tumours
originating from neuroendocrine cells found throughout the body. Pancreatic NENs …

Pancreatic neuroendocrine neoplasms (PanNENs) contain two primary subtypes with
distinct molecular features and associated clinical outcomes: well-differentiated …

Purpose We assessed the usefulness of real-time molecular profiling through next-
generation sequencing (NGS) in predicting the tumor biology of advanced pancreatic …

Primary non‐functional pancreatic neuroendocrine tumors (NF‐PanNETs) are a
heterogeneous group of neuroendocrine neoplasms that display highly variable clinical …

AIM: To investigate the prognostic role of genomic stability and copy number alterations
(CNAs) pancreatic neuroendocrine tumors (PanNETs). METHODS: A high-resolution array …