New insights into the structure and function of fatty acid-binding proteins

AW Zimmerman, JH Veerkamp - Cellular and Molecular Life Sciences …, 2002 - Springer
Fatty acid-binding proteins (FABPs) are members of a superfamily of lipid-binding proteins,
and occur intracellularly in vertebrates and invertebrates. This review presents recent …

Tissue-specific functions in the fatty acid-binding protein family

J Storch, AE Thumser - Journal of Biological Chemistry, 2010 - ASBMB
The intracellular fatty acid-binding proteins (FABPs) are abundantly expressed in almost all
tissues. They exhibit high affinity binding of a single long-chain fatty acid, with the exception …

The emerging functions and mechanisms of mammalian fatty acid–binding proteins

J Storch, B Corsico - Annu. Rev. Nutr., 2008 - annualreviews.org
Fatty acid–binding proteins (FABPs) are abundant intracellular proteins that bind long-chain
fatty acids with high affinity. Nine separate mammalian FABPs have been identified, and …

Fatty acid-binding proteins–insights from genetic manipulations

NH Haunerland, F Spener - Progress in lipid research, 2004 - Elsevier
Fatty acid-binding proteins (FABPs) belong to the conserved multigene family of the
intracellular lipid-binding proteins (iLBPs). These proteins are ubiquitously expressed in …

Cytoplasmic fatty acid-binding proteins: emerging roles in metabolism and atherosclerosis

JB Boord, S Fazio, MRF Linton - Current opinion in lipidology, 2002 - journals.lww.com
Cytoplasmic fatty acid-binding proteins (FABPs) are a family of proteins, expressed in a
tissue-specific manner, that bind fatty acid ligands and are involved in shuttling fatty acids to …

SnapShot: FABP functions

B Li, J Hao, J Zeng, ER Sauter - Cell, 2020 - cell.com
Fatty acid binding proteins (FABPs) serve as intracellular chaperones for fatty acids and
other hydrophobic ligands inside cells. Recent studies have demonstrated new functions of …

The human fatty acid-binding protein family: evolutionary divergences and functions

RL Smathers, DR Petersen - Human genomics, 2011 - Springer
Fatty acid-binding proteins (FABPs) are members of the intracellular lipid-binding protein
(iLBP) family and are involved in reversibly binding intracellular hydrophobic ligands and …

Fatty acid binding protein: localization and functional significance in the brain

Y Owada - The Tohoku journal of experimental medicine, 2008 - jstage.jst.go.jp
Long chain fatty acids are important nutrients for brain development and function. However,
the molecular basis of their actions in the brain is still to be clarifi ed. Fatty acidbinding …

Role of fatty acid binding proteins (FABPs) in cancer development and progression

IH McKillop, CA Girardi, KJ Thompson - Cellular signalling, 2019 - Elsevier
Fatty acid binding proteins (FABPs) are small, water soluble proteins that bind long chain
fatty acids and other biologically active ligands to facilitate intracellular localization. Twelve …

The cellular fatty acid binding proteins: aspects of structure, regulation, and function

NM Bass - International review of cytology, 1988 - Elsevier
Publisher Summary This chapter provides a comprehensive overview of the current state of
knowledge of the research with particular emphasis on evolving concepts of fatty acid …