Tooth agenesis constitutes the most common anomaly of dental development in humans. In
the majority of familial cases of hypodontia alone or in association with other anomalies, the …

Tooth agenesis is one of the most common craniofacial disorders in humans. More than 350
genes have been associated with teeth development. In this study, we enrolled 60 child …

Oligodontia, which is the congenital absence of six or more permanent teeth, excluding the
third molars, may contribute to masticatory dysfunction, speech alteration, aesthetic …

OBJECTIVES: Oligodontia is defined as the congenital absence of 6 or more permanent
teeth excluding the third molar. The occurrence of non-syndromic still remains poorly …

The goal of this study was to identify MSX1 gene variants in multiple Chinese families with
nonsyndromic oligodontia and analyse the functional influence of these variants. Whole …

Even though selective tooth agenesis is the most common developmental anomaly of
human dentition, its genetic background still remains poorly understood. To date, familial as …

A frameshift mutation recently identified within the paired domain of the transcription factor,
PAX9, has been linked to a unique form of oligodontia in a single, multigenerational family …

OBJECTIVE: Recently, several genes have been reported with mutations or variants that
underlie a number of syndromic and non-syndromic forms of oligodontia including MSX1 …

Multiple previous reports confirm that several missense alleles of MSX1 exhibit Mendelian
inheritance of an oligodontia phenotype (agenesis of more than six secondary teeth besides …

Objectives In this study, the aim was to investigate a consanguineous Saudi family with non-
syndromic premolars and third molars agenesis and to identify the causal mutation (s) using …