The importance of hope has long been recognized, whereas a lack of hope, or “giving up,” is
generally believed to have a negative impact on psychological well-being and physical …

Recent studies have reported that hopelessness is an important factor in cardiovascular
morbidity and mortality, including ischemic heart disease, acute myocardial infarction, and …

Background and Purpose—Depression and hopelessness are associated with increased
cardiovascular disease (CVD) morbidity and mortality; however, few studies have compared …

Objective: Optimistic people report a higher quality of life, engage in more active coping and
adopt more health-promoting behaviors than people low in optimism, ie, pessimism. We …

Objective: To examine whether the psychological traits of hopelessness and depressive
symptoms are related to endothelial dysfunction. Methods: Data are derived from a …

Objective: To investigate the association between optimism/pessimism and concentrations
of seven inflammation and hemostasis markers. Optimism and pessimism are associated …

Background and Purpose—The association between optimism and pessimism and health
outcomes has attracted increasing research interest. To date, the association between these …

We examined the relationship among low, moderate, and high levels of hopelessness, all-
cause and cause-specific mortality, and incidence of myocardial infarction (MI) and cancer in …

Background: Recent research suggests that optimism may reduce the risk of incident
cardiovascular disease, but the mechanisms have not been determined. This study …

Objective: We examined the independent association between dispositional optimism
compared to dispositional pessimism and ideal cardiovascular health (defined by the …