Complement not only plays a key role in host microbial defense but also modulates the
adaptive immune response through modification of T-and B-cell reactivity. Moreover, a …

Complement immunobiology, and with it complement analysis, has undergone a
renaissance in the past decade. Classically, complement analysis was limited number of …

In recent years, complement analysis of body fluids and biopsies, going far beyond C3 and
C4, has significantly enhanced our understanding of the disease process. Such expanded …

The complement system is the human's first line of defense against microbial pathogens
because of its important housekeeping and infection/inflammation roles. It is composed of a …

The complement system plays an important role in varying types of disease, ranging from
inflammatory and autoimmune disorders to immune deficiency states. In addition, new …

Complement system aberrations have been identified as pathophysiological mechanisms in
a number of diseases and pathological conditions either directly or indirectly. Examples of …

Aberrations in complement system functions have been identified as either direct or indirect
pathophysiological mechanisms in many diseases and pathological conditions, such as …

Complement is a complex system. This complexity becomes more obvious when looking at
complement analysis in health and disease, where one presentation can require a number …

Complement has long been considered a key innate immune effector system that mediates
host defence and tissue homeostasis. Yet, growing evidence has illuminated a broader …

The ability of the complement system to rapidly and broadly react to microbial intruders,
apoptotic cells and other threats by inducing forceful elimination responses is indispensable …