Updates in the pathology of penile intraepithelial neoplasia

GA Giannico, AL Cubilla - Diagnostic Histopathology, 2023 - Elsevier
Penile intraepithelial neoplasia (PeIN) is the putative histologic precursor of penile
squamous cell carcinoma. PeIN is classified into HPV-associated and HPV-independent …

[HTML][HTML] Pathological characterization and clinical outcome of penile intraepithelial neoplasia variants: a North American series

MMS Hogan, AJ Spieker, M Orejudos, T Gheit, M Herfs… - Modern Pathology, 2022 - Elsevier
Penile intraepithelial neoplasia (PeIN) is classified as human papillomavirus (HPV)-and non-
HPV-related. This classification is associated with distinct morphologic subtypes. The natural …

Histologic classification of penile intraepithelial neoplasia

EF Velazquez, A Chaux, AL Cubilla - Seminars in diagnostic pathology, 2012 - Elsevier
Penile squamous cell carcinomas (SCCs) and their corresponding precancerous lesions
can be classified in 2 major groups: human papillomavirus (HPV) related and HPV …

The management of penile intraepithelial neoplasia (PeIN): clinical and histological features and treatment of 345 patients and a review of the literature

G Kravvas, L Ge, J Ng, TN Shim… - Journal of …, 2022 - Taylor & Francis
Abstract Introduction Penile intraepithelial neoplasia (PeIN) is a histological term for
precancerous penile lesions. PeIN is important due to the high morbidity and mortality …

Penile intraepithelial neoplasia: Distribution of subtypes, HPV genotypes and p16INK4a in 84 international cases

MJ Fernández-Nestosa, O Clavero, DF Sánchez… - Human Pathology, 2023 - Elsevier
There are few pathologic or molecular studies of penile precancerous lesions, and the
majority refers to lesions associated with invasive carcinomas. Penile Intraepithelial …

The spectrum of HPV-independent penile intraepithelial neoplasia: a proposal for subclassification

S Regauer, M Ermakov, K Kashofer - The American Journal of …, 2023 - journals.lww.com
Compared with vulva, precursor lesions of human papillomavirus (HPV)-independent
invasive squamous cell carcinoma (SCC) of the penis are insufficiently characterized. We …

Penile intraepithelial neoplasia: management and outcomes

A Zreik, M Ismail, R Nigam - Human Andrology, 2013 - journals.lww.com
Background Penile cancer is a rare malignancy that affects 1 in 100 000 men. Penile
intraepithelial neoplasia (PeIN) is a premalignant lesion that can affect any part of the penile …

Distinctive immunohistochemical profile of penile intraepithelial lesions: a study of 74 cases

A Chaux, R Pfannl, IM Rodríguez… - The American journal …, 2011 - journals.lww.com
Several classification schemes for penile precancerous lesions have been proposed, but
none of them seems to correlate with the current understanding of penile cancer …

Comparison of human papillomavirus genotypes in penile intraepithelial neoplasia and associated lesions: LCM-PCR study of 87 lesions in 8 patients

MJ Fernández-Nestosa, N Guimerà… - … Journal of Surgical …, 2020 - journals.sagepub.com
Penile intraepithelial neoplasia (PeIN) is currently classified in human papillomavirus (HPV)-
and non-HPV-related subtypes with variable HPV genotypes. PeINs are frequently …

Advances in the pathology of penile carcinomas

A Chaux, AL Cubilla - Human pathology, 2012 - Elsevier
The incidence of penile cancer varies from country to country, with the highest figures
reported for countries in Africa, South America, and Asia and lowest in the United States and …