CRISPR‐Cas9 technology and its application in haematological disorders
H Zhang, N McCarty - British journal of haematology, 2016 - Wiley Online Library
The recent advent of the Clustered Regularly Interspaced Short Palindromic Repeats
(CRISPR)‐CRISPR associated protein 9 (Cas9) system for precise genome editing has …
(CRISPR)‐CRISPR associated protein 9 (Cas9) system for precise genome editing has …
[HTML][HTML] RNA-guided CRISPR-Cas technologies for genome-scale investigation of disease processes
SE Humphrey, AL Kasinski - Journal of hematology & oncology, 2015 - Springer
From its discovery as an adaptive bacterial and archaea immune system, the clustered
regularly interspaced short palindromic repeats (CRISPR)-Cas system has quickly been …
regularly interspaced short palindromic repeats (CRISPR)-Cas system has quickly been …
Clinical applications of CRISPR‐based genome editing and diagnostics
Clustered regularly interspaced short palindromic repeats (CRISPR)‐driven genome editing
has rapidly transformed preclinical biomedical research by eliminating the underlying …
has rapidly transformed preclinical biomedical research by eliminating the underlying …
Mini review: genome and transcriptome editing using CRISPR-cas systems for haematological malignancy gene therapy
EK Elliott, LM Haupt, LR Griffiths - Transgenic Research, 2021 - Springer
The recent introduction of clustered regularly interspaced short palindromic repeats
(CRISPR) and CRISPR associated protein (Cas) systems, offer an array of genome and …
(CRISPR) and CRISPR associated protein (Cas) systems, offer an array of genome and …
Genome editing using CRISPR/Cas9 to treat hereditary hematological disorders
Y Chen, R Wen, Z Yang, Z Chen - Gene Therapy, 2022 - nature.com
The clustered regularly interspaced short palindromic repeats/CRISPR-associated protein 9
(CRISPR/Cas9) system is a versatile and convenient genome-editing tool with prospects in …
(CRISPR/Cas9) system is a versatile and convenient genome-editing tool with prospects in …
[HTML][HTML] CRISPR-Based Gene Therapies: From Preclinical to Clinical Treatments
In recent years, clustered regularly interspaced short palindromic repeats (CRISPRs) and
CRISPR-associated (Cas) protein have emerged as a revolutionary gene editing tool to treat …
CRISPR-associated (Cas) protein have emerged as a revolutionary gene editing tool to treat …
A CRISPR view of hematopoietic stem cells: moving innovative bioengineering into the clinic
AK Worthington, EC Forsberg - American journal of hematology, 2022 - Wiley Online Library
Clustered regularly interspaced short palindromic repeats (CRISPR)/Cas genome
engineering has emerged as a powerful tool to modify precise genomic sequences with …
engineering has emerged as a powerful tool to modify precise genomic sequences with …
[HTML][HTML] CRISPR/Cas9 genome engineering in hematopoietic cells
D Sürün, H von Melchner, F Schnütgen - Drug Discovery Today …, 2018 - Elsevier
The development of genome editing tools capable of modifying specific genomic sequences
with unprecedented accuracy has opened up a wide range of new possibilities in targeted …
with unprecedented accuracy has opened up a wide range of new possibilities in targeted …
[HTML][HTML] CRISPR/Cas9 and TALE: beyond cut and paste
L Deng, R Ren, J Wu, K Suzuki, JC Izpisua Belmote… - Protein & Cell, 2015 - Springer
Nuclease-based genome editing has proven to be a powerful and promising tool for disease
modeling and gene therapy. Recent advances in CRISPR/Cas and TALE indicate that they …
modeling and gene therapy. Recent advances in CRISPR/Cas and TALE indicate that they …
Gene editing and CRISPR in the clinic: current and future perspectives
Genome editing technologies, particularly those based on zinc-finger nucleases (ZFNs),
transcription activator-like effector nucleases (TALENs), and CRISPR (clustered regularly …
transcription activator-like effector nucleases (TALENs), and CRISPR (clustered regularly …