Genome editing via homologous recombination (HR)(gene targeting) in human
hematopoietic stem cells (HSCs) has the power to reveal gene–function relationships and …

Base editors, developed from the CRISPR/Cas system, consist of components such as
deaminase and Cas variants. Since their emergence in 2016, the precision, efficiency, and …

Programmable nucleases including zinc finger nucleases, transcription activator-like effector
nucleases, and clustered regularly interspaced short palindrome repeats (CRISPR)/CRISPR …

The clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-
associated protein 9 (Cas9)(CRISPR/Cas9) system is a powerful tool that enables precise …

The development of CRISPR-derived genome editing technologies has enabled the precise
manipulation of DNA sequences within the human genome. In this review, we discuss the …

Programmable nucleases, such as zinc finger nucleases (ZFNs), transcription activator like
effector nucleases (TALENs), and clustered regularly interspersed short palindromic repeats …

The clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 system has
revolutionized the gene editing field, making it possible to interrupt, insert or replace a …

Modern genetic therapy incorporates genomic testing and genome editing. It is the finest
approach for precision medicine. Genome editing is a state‐of‐the‐art technology to …

In the field of hematology, gene therapies based on integrating vectors have reached
outstanding results for a number of human diseases. With the advent of novel programmable …

The recent development of the CRISPR/Cas9 system as an efficient and accessible
programmable genome‐editing tool has revolutionized basic science research …