Human cytomegalovirus resistance to antiviral drugs: diagnosis, monitoring and clinical impact

F Baldanti, G Gerna - Journal of Antimicrobial Chemotherapy, 2003 - academic.oup.com
The incidence of human cytomegalovirus (HCMV) disease in AIDS patients decreased
dramatically after the introduction, a few years ago, of highly active antiretroviral combination …

Clinical and biologic aspects of human cytomegalovirus resistance to antiviral drugs

F Baldanti, N Lurain, G Gerna - Human immunology, 2004 - Elsevier
The emergence of human cytomegalovirus (HCMV) drug resistant strains is a life-
threatening condition in immunocompromised individuals with active HCMV infection …

Human cytomegalovirus resistance to antiviral drugs

C Gilbert, G Boivin - Antimicrobial Agents and Chemotherapy, 2005 - Am Soc Microbiol
Human cytomegalovirus (HCMV) infections are common and lead to lifelong infections. In
immunocompetent individuals, primary infections are mostly subclinical or they may be …

How evolution of mutations conferring drug resistance affects viral dynamics and clinical outcomes of cytomegalovirus-infected hematopoietic cell transplant recipients

KL Springer, S Chou, S Li, RH Giller… - Journal of Clinical …, 2005 - Am Soc Microbiol
Infection with cytomegalovirus (CMV) remains a significant cause of morbidity and mortality
among hematopoietic cell transplant (HCT) recipients. We describe two pediatric HCT …

High rate of cytomegalovirus drug resistance among patients receiving preemptive antiviral treatment after haploidentical stem cell transplantation

E Shmueli, R Or, MY Shapira, IB Resnick… - The Journal of …, 2014 - academic.oup.com
We examined the rate, clinical impact, and risk factors of cytomegalovirus (CMV) drug
resistance in 561 patients who underwent 616 hematopoietic stem cell transplantations …

Resistance of human cytomegalovirus to antiviral drugs

A Erice - Clinical Microbiology Reviews, 1999 - Am Soc Microbiol
Resistance of cytomegalovirus (CMV) to antiviral agents is a well-recognized phenomenon
that has been observed in the laboratory and in the clinical setting. Infections caused by …

Approach to drug-resistant cytomegalovirus in transplant recipients

S Chou - Current opinion in infectious diseases, 2015 - journals.lww.com
Technical advancements can enhance the accurate and timely genotypic detection of drug
resistance. Antivirals undergoing clinical trial offer the prospect of new viral targets and drug …

[HTML][HTML] Cytomegalovirus antiviral drug resistance: future prospects for prevention, detection and management

KE Hanson, S Swaminathan - Future Microbiology, 2015 - Future Medicine
Human cytomegalovirus (CMV) is one of the most important viral pathogens affecting
hematopoietic stem cell transplant (HSCT) and solid organ transplant (SOT) recipients …

Diversity of antiviral‐resistant human cytomegalovirus in heart and lung transplant recipients

JM Iwasenko, GM Scott, Z Naing… - Transplant Infectious …, 2011 - Wiley Online Library
JM Iwasenko, GM Scott, Z. Naing, AR Glanville, WD Rawlinson. Diversity of antiviral‐
resistant human cytomegalovirus in heart and lung transplant recipients. Transpl Infect Dis …

Human cytomegalovirus double resistance in a donor-positive/recipient-negative lung transplant patient with an impaired CD4-mediated specific immune response

F Baldanti, D Lilleri, G Campanini… - Journal of …, 2004 - academic.oup.com
Background: Emergence of human cytomegalovirus (HCMV) resistance to ganciclovir in
solid-organ transplant recipients has been found to be mostly associated with primary …