Resistance to antivirals in human cytomegalovirus: mechanisms and clinical significance.
JL Perez - Microbiologia (Madrid, Spain), 1997 - europepmc.org
Long term therapies needed for managing human cytomegalovirus (HCMV) infections in
immunosupressed patients provided the background for the emergence of the resistance to …
immunosupressed patients provided the background for the emergence of the resistance to …
Global estimate of phenotypic and genotypic ganciclovir resistance in cytomegalovirus infections among HIV and organ transplant patients; A systematic review and …
Human cytomegalovirus (CMV), an opportunistic pathogen belonging to Herpesviridae
family, is considered as one of the major causes of morbidity and mortality among wide …
family, is considered as one of the major causes of morbidity and mortality among wide …
The biology of cytomegalovirus drug resistance
M Hakki, S Chou - Current opinion in infectious diseases, 2011 - journals.lww.com
An increasing volume of information correlating CMV genotypes and drug susceptibility
phenotypes is becoming available. This will improve the interpretation of sequence-based …
phenotypes is becoming available. This will improve the interpretation of sequence-based …
Emergence of multiple drug-resistant human cytomegalovirus variants in 2 patients with human immunodeficiency virus infection unresponsive to highly active …
F Baldanti, S Paolucci, A Parisi… - Clinical infectious …, 2002 - academic.oup.com
In 2 patients infected with human immunodeficiency virus (HIV), highly active antiretroviral
therapy was unable to suppress HIV replication as a result of the emergence of drug …
therapy was unable to suppress HIV replication as a result of the emergence of drug …
Cytomegalovirus resistance in solid organ transplant recipients treated with intravenous ganciclovir or oral valganciclovir
Background The rate of cytomegalovirus (CMV) mutations conferring ganciclovir resistance
was assessed in a trial comparing intravenous ganciclovir and oral valganciclovir for …
was assessed in a trial comparing intravenous ganciclovir and oral valganciclovir for …
Emergence and persistence of multiple antiviral-resistant CMV strains in a highly immunocompromised child
JM Iwasenko, GM Scott, JB Ziegler… - Journal of clinical …, 2007 - Elsevier
BACKGROUND: The emergence of human cytomegalovirus (CMV) antiviral resistance plays
a significant role in disease progression in immunocompromised patients who have …
a significant role in disease progression in immunocompromised patients who have …
A new tool linking human cytomegalovirus drug resistance mutations to resistance phenotypes
M Chevillotte, J von Einem, BM Meier, FM Lin… - Antiviral research, 2010 - Elsevier
Drug resistant strains of human cytomegalovirus (HCMV) in patients at risk may increasingly
develop into a problem in the clinical setting. Genotypic resistance testing is becoming the …
develop into a problem in the clinical setting. Genotypic resistance testing is becoming the …
Fatal reactivation of postnatal cytomegalovirus infection with rapid emergence of ganciclovir resistance in an infant after allogeneic stem cell transplantation
S Voigt, D Michel, O Kershaw, JS Kühl… - Journal of clinical …, 2005 - Am Soc Microbiol
Human cytomegalovirus (HCMV) can cause serious problems after hematopoietic stem cell
transplantation. The death of a pediatric transplant recipient after reactivation of a postnatal …
transplantation. The death of a pediatric transplant recipient after reactivation of a postnatal …
Multidrug resistance conferred by novel DNA polymerase mutations in human cytomegalovirus isolates
GM Scott, A Weinberg, WD Rawlinson… - Antimicrobial agents …, 2007 - Am Soc Microbiol
The emergence of antiviral-resistant cytomegalovirus (CMV) strains is a continuing clinical
problem, with increased numbers of immunocompromised patients given longer-duration …
problem, with increased numbers of immunocompromised patients given longer-duration …