[HTML][HTML] Sanguinarine inhibits the proliferation of BGC-823 gastric cancer cells via regulating miR-96-5p/miR-29c-3p and the MAPK/JNK signaling pathway
XZ Dong, Y Song, YP Lu, Y Hu, P Liu… - Journal of natural …, 2019 - Springer
Sanguinarine (SAN), a quaternary benzophenanthridine alkaloid extracted from the root of
Papaveraceae plants, has shown antitumour effects in multiple cancer cells. However, the …
Papaveraceae plants, has shown antitumour effects in multiple cancer cells. However, the …
Sanguinarine inhibits growth and invasion of gastric cancer cells via regulation of the DUSP4/ERK pathway
R Zhang, G Wang, PF Zhang, J Zhang… - Journal of cellular …, 2017 - Wiley Online Library
Sanguinarine, a bioactive benzophenanthridine alkaloid extracted from plants of the
Papaveraceae family, has shown antitumour effects in multiple cancer cells. But the …
Papaveraceae family, has shown antitumour effects in multiple cancer cells. But the …
[HTML][HTML] Sanguinarine-induced apoptosis in lung adenocarcinoma cells is dependent on reactive oxygen species production and endoplasmic reticulum stress
Sanguinarine (SAN), an alkaloid isolated from plants of the Papaveraceae family, is a
compound with multiple biological activities. In the present study, we explored the anticancer …
compound with multiple biological activities. In the present study, we explored the anticancer …
Anticancer potential of sanguinarine for various human malignancies
Sanguinarine (Sang)–a benzophenanthridine alkaloid extracted from Sanguinaria
canadensis–exhibits antioxidant, anti-inflammatory, proapoptotic and growth inhibitory …
canadensis–exhibits antioxidant, anti-inflammatory, proapoptotic and growth inhibitory …
Sanguinarine: a double-edged sword of anticancer and carcinogenesis and its future application prospect
G Lou, J Wang, J Hu, Q Gan, C Peng… - Anti-Cancer Agents …, 2021 - ingentaconnect.com
Background: Sanguinarine, a kind of benzophenanthridine alkaloid, is a natural compound
with potential development value for its anticancer activity. Hundreds of studies have been …
with potential development value for its anticancer activity. Hundreds of studies have been …
Molecular mechanisms of Sanguinarine in cancer prevention and treatment
Historically, natural plant-derived drugs received a great impact of consideration in the
treatment of several human-associated disorders. Cancer is a devastating disease and the …
treatment of several human-associated disorders. Cancer is a devastating disease and the …
[HTML][HTML] Antitumor effects of the benzophenanthridine alkaloid sanguinarine: Evidence and perspectives
R Gaziano, G Moroni, C Buè, MT Miele… - World Journal of …, 2016 - ncbi.nlm.nih.gov
Historically, natural products have represented a significant source of anticancer agents,
with plant-derived drugs becoming increasingly explored. In particular, sanguinarine is a …
with plant-derived drugs becoming increasingly explored. In particular, sanguinarine is a …
Molecular targets and anticancer potential of sanguinarine—A benzophenanthridine alkaloid
Background Cancer is an enormous global health burden, and should be effectively
addressed with better therapeutic strategies. Currently, over 60% of the clinically approved …
addressed with better therapeutic strategies. Currently, over 60% of the clinically approved …
[HTML][HTML] Sanguinarine inhibits growth of human cervical cancer cells through the induction of apoptosis
JY Xu, QH Meng, Y Chong, Y Jiao… - Oncology …, 2012 - spandidos-publications.com
Sanguinarine, a natural benzophenanthridine alkaloid, has been shown to possess
anticancer activity in vitro and in vivo. In the present study, we demonstrated that …
anticancer activity in vitro and in vivo. In the present study, we demonstrated that …
Sanguinarine induces apoptosis of HT-29 human colon cancer cells via the regulation of Bax/Bcl-2 ratio and caspase-9-dependent pathway
Sanguinarine is an alkaloid obtained from the bloodroot plant Sanguinaria canadensis and
has beneficial effects on oxidative stress and inflammatory disorders. Previous reports have …
has beneficial effects on oxidative stress and inflammatory disorders. Previous reports have …