Objectives: It is aimed to determine the association between four single-nucleotide
polymorphisms (SNPs) of IL1 genes (rs1800587: IL1A− 889 C/T, rs16944: IL1B− 511 T/C …

Abstract Background and Aim Interleukin (IL)-1 family members play an important role in the
pathogenesis of inflammatory bowel disease (IBD). There are conflicting results regarding …

1. Introduction. Multiple cytokines have been studied for their role in the propagation of the
inflammatory process related to inflammatory bowel diseases (IBD), but the role of …

Background: Changes in cytokine expression have been frequently found in patients with
inflammatory bowel disease (IBD). Cytokine values outside the normal range may be …

The frequencies of alleles and genotypes of TNF-α, TNF-β, and IL-10 genes were examined
in Saudi subjects including IBD patients (UC and CD) and matched controls. Venous blood …

Inflammatory bowel disease (IBD), which includes Crohn's disease (CD) and ulcerative
colitis (UC), represents a group of chronic inflammatory disorders caused by dysregulated …

Objective. Crohn's disease (CD) and ulcerative colitis (UC) are chronic inflammatory
diseases of the bowel, the causes of which are not fully known. Ethnic differences in disease …

BACKGROUND: Several studies have tried to find possible associations between genetic
polymorphisms and inflammatory bowel disease prevalence and/or phenotype. Our …

Background—An imbalance between the proinflammatory cytokine interleukin 1β (IL-1β)
and the anti-inflammatory cytokine IL-1 receptor antagonist (IL-1ra) has been postulated as …

Objective: Genetic susceptibility to inflammatory bowel disease is well recognized. There is
also increasing evidence for the activation of the mucosal immune system and the …