[HTML][HTML] Predominant Api m 10 sensitization as risk factor for treatment failure in honey bee venom immunotherapy

M Frick, J Fischer, A Helbling, F Ruëff… - Journal of allergy and …, 2016 - Elsevier
Background Component resolution recently identified distinct sensitization profiles in honey
bee venom (HBV) allergy, some of which were dominated by specific IgE to Api m 3 and/or …

[HTML][HTML] Component resolution reveals additional major allergens in patients with honeybee venom allergy

J Köhler, S Blank, S Müller, F Bantleon, M Frick… - Journal of allergy and …, 2014 - Elsevier
Background Detection of IgE to recombinant Hymenoptera venom allergens has been
suggested to improve the diagnostic precision in Hymenoptera venom allergy. However, the …

Immunological and clinical factors associated with adverse systemic reactions during the build‐up phase of honeybee venom immunotherapy

P Korošec, K Žiberna, M Šilar… - Clinical & …, 2015 - Wiley Online Library
Background Adverse systemic reactions (SR s) are more common in honeybee venom
immunotherapy (VIT) than in wasp VIT. Factors that might be associated with SR s during the …

Component-resolved evaluation of the content of major allergens in therapeutic extracts for specific immunotherapy of honeybee venom allergy

S Blank, S Etzold, U Darsow, M Schiener… - Human Vaccines & …, 2017 - Taylor & Francis
Allergen-specific immunotherapy is the only curative treatment of honeybee venom (HBV)
allergy, which is able to protect against further anaphylactic sting reactions. Recent analyses …

[HTML][HTML] The honeybee venom major allergen Api m 10 (Icarapin) and its role in diagnostics and treatment of hymenoptera venom allergy

T Jakob, MM Rauber, A Perez-Riverol… - Current Allergy and …, 2020 - Springer
Abstract Purpose of Review In Hymenoptera venom allergy, the research focus has moved
from whole venoms to individual allergenic molecules. Api m 10 (icarapin) has been …

rA pi m 3 and rA pi m 10 improve detection of honey bee sensitization in Hymenoptera venom‐allergic patients with double sensitization to honey bee and yellow …

M Frick, S Müller, F Bantleon, J Huss‐Marp, J Lidholm… - Allergy, 2015 - Wiley Online Library
Recombinant allergens improve the diagnostic precision in Hymenoptera venom allergy
(HVA), in particular in patients with double sensitization to both honey bee (HBV) and yellow …

Clinical and immunologic effects of H1 antihistamine preventive medication during honeybee venom immunotherapy

UR Müller, M Jutel, A Reimers, J Zumkehr… - Journal of allergy and …, 2008 - Elsevier
BACKGROUND: H1 antihistamines increase safety during allergen-specific immunotherapy
and might influence the outcome because of immunoregulatory effects. OBJECTIVE: We …

IgE-Api m 4 is useful for identifying a particular phenotype of bee venom allergy.

B Ruiz, P Serrano, C Moreno - Journal of Investigational …, 2016 - europepmc.org
Methods Prospective study of 31 patients allergic to bee venom who were assigned to
phenotype group A (sIgE-Api m 4< 0.98 kU/L), treated with native aqueous (NA) extract, or …

[HTML][HTML] The culprit insect but not severity of allergic reactions to bee and wasp venom can be determined by molecular diagnosis

P Gattinger, C Lupinek, L Kalogiros, M Silar, M Zidarn… - PLoS …, 2018 - journals.plos.org
Background Allergy to bee and wasp venom can lead to life-threatening systemic reactions.
The identification of the culprit species is important for allergen-specific immunotherapy …

Predictive value of venom‐specific IgE, IgG and IgG subclass antibodies in patients on immunotherapy with honey bee venom

U Müller, A Helbling, M Bischof - Allergy, 1989 - Wiley Online Library
Sixty‐seven patients with a history of severe systemic reactions following honey bee stings
were treated by immunotherapy (IT) with honey bee venom. During maintenance therapy all …