A highly sulfated chondroitin sulfate, CS-E, prevents excitatory amino acid-induced neuronal
cell death by an as yet unknown mechanism. To reveal this mechanism, we pretreated …

J. Neurochem.(2008) 104, 1565–1576. Abstract Chondroitin sulfate (CS) is a major
microenvironmental molecule in the CNS, and there have been few reports about its …

Chondroitin sulfate (CS) plays critical roles in central nervous system development and
regeneration, and individual modifications of CS form a" sulfation code" that regulates …

The role of chondroitin sulfate proteoglycans (CSPGs) on excitotoxic cell death and long-
term survival of neurons were investigated in primary cultured neurons of the rat cortex …

Chondroitin sulfate (CS) expression is increased in the glial scar following spinal cord injury
demonstrating the importance understanding the role of CS in the central nervous system …

Chondroitin sulfate proteoglycans (CSPGs), up-regulated in and around the glial scar after
mammalian spinal cord injury, have been suggested to be key inhibitory molecules for …

Protective effects of chondroitin sulfate proteoglycans (CSPGs) from rat's brain against
delayed cell death induced by excitatory amino acids were examined in cultured neurons of …

Abstract Tenascin‐R (TN‐R), an extracellular matrix constituent of the central nervous
system (CNS), has been implicated in a variety of cell–matrix interactions underlying axon …

We have discovered that N-acetyl-L-cysteine (NAC) protects cells against death induced by
exposure to noxious stimuli and against programmed cell death (apoptosis) associated with …

The extracellular matrix (ECM) of the central nervous system (CNS) occupies a large part of
the neural tissue. It serves a variety of functions ranging from support of cell migration and …