Dental calculus (DC) is a common deposit in periodontitis patients. We have previously
shown that DC contains both microbial components and calcium phosphate crystals that …

In inflammatory bone diseases such as periodontitis, the nucleotide-binding oligomerization
domain, leucine-rich repeat, and pyrin domain-containing 3 (NLRP3) inflammasome …

This study investigates the role of NLRP3 inflammasome and its main effector Caspase-1 in
inflammation and alveolar bone resorption associated with periodontitis. Heat-killed …

There is virtually no information on the role of NLRC4 inflammasome on bone resorption
and inflammation associated with periodontitis. Bacterial-associated experimental …

Dental calculus is a mineralized deposit associated with periodontitis. The bacterial
components contained in dental calculus can be recognized by host immune sensors, such …

Objective We aim to investigate whether lipopolysaccharide-stimulated activition of Nod-like
receptor protein 3 (NLRP3) Inflammasome inhibits osteogenesis in Human periodontal …

Objectives NLRP3 inflammasome is a critical part of the innate immune system and plays an
important role in a variety of inflammatory diseases. However, the effects of NLRP3 …

The cause of chronic inflammatory periodontitis, which leads to the destruction of
periodontal ligament and alveolar bone, is multifactorial. An increasing number of studies …

Prolonged inflammation continuously promotes the infiltration of macrophages in the
organization and chronically induces the production of pro-inflammatory cytokines such as …

Background The NLRP3 inflammasome plays an important role in the cellular defense
against invading pathogens and is reported to be expressed in human dental pulp …