Background and aims Hepatocellular carcinomas (HCCs) are heterogeneous aggressive
tumors with low rates of response to treatment at advanced stages. We screened a large …

Purpose: The outcome of patients with advanced hepatocellular carcinoma (HCC) has
remained unsatisfactory. Patients with HCC suffer from chronic hepatitis or liver cirrhosis …

Hepatocellular carcinoma (HCC) is a common malignancy and one of the leading causes of
cancer-related death. The biological process of HCC is complex, with multiple factors …

Hepatocellular carcinoma (HCC) is the most prevalent primary liver cancer and a leading
cause of cancer-related deaths worldwide. Ninety percent of HCC cases arise from cirrhosis …

Hepatocellular carcinomas (HCCs) are characterised by considerable phenotypic and
molecular heterogeneity. Treating HCC and designing clinical trials are particularly …

Despite great progress in diagnosis and management of hepatocellular carcinoma (HCC),
the exact biology of the tumor remains poorly understood overall limiting the patients' …

Molecular characterization of hepatocellular carcinoma (HCC) has greatly improved our
understanding of disease pathogenesis. Mutational analysis, RNA and microRNA …

Purpose: Prior molecular profiling of hepatocellular carcinoma (HCC) has identified
actionable findings that may have a role in guiding therapeutic decision-making and clinical …

Background & Aims No targeted therapies have been found to be effective against
hepatocellular carcinoma (HCC), possibly due to the large degree of intratumor …

Hepatocellular carcinoma (HCC) is one of the most prevalent and fatal digestive tumors.
Treatment for this disease has been constraint by heterogeneity of this group of tumors …