[HTML][HTML] Potential role of selenium in modifying the effect of maternal methylmercury exposure on child neurodevelopment–A review

M Wesolowska, AJ Yeates, EM McSorley… - Neurotoxicology, 2023 - Elsevier
Selenium (Se) is an essential trace element for normal neurodevelopment. It is incorporated
into multiple selenoenzymes which have roles in the brain and neurological function, the …

Methylmercury and brain development: imprecision and underestimation of developmental neurotoxicity in humans

P Grandjean, KT Herz - Mount Sinai Journal of Medicine: A …, 2011 - Wiley Online Library
Methylmercury is now recognized as an important developmental neurotoxicant, though this
insight developed slowly over many decades. Developmental neurotoxicity was first …

Delayed neurochemical effects of prenatal exposure to MeHg in the cerebellum of developing rats

L Heimfarth, J Delgado, MR Mingori, KS Moresco… - Toxicology letters, 2018 - Elsevier
Human fetuses and neonates are particularly vulnerable to methylmercury (MeHg)-induced
brain damage and are sensitive even to low exposure levels. Previous work of our group …

Adult brain nitrergic activity after concomitant prenatal exposure to ethanol and methyl mercury

CSF Maia, VMM Ferreira, RL Kahwage, MN do Amaral… - Acta histochemica, 2010 - Elsevier
Pregnant rats were exposed to ethanol (EtOH) and/or methyl mercury (MeHg) during fetal
brain development. Nitrergic activity was quantified by densitometric measurement of …

Effects of methylmercury on postnatal neurobehavioral development in mice

Y Gao, Y Ding, R Shi, Y Tian - Neurotoxicology and teratology, 2008 - Elsevier
Eighty ICR mice were randomly assigned to one of four groups given daily intraperitoneal
injections of 0, 0.1, 1 or 3 mg/kg MeHg chloride respectively from postnatal days (PD) 15–17 …

Does background postnatal methyl mercury exposure in toddlers affect cognition and behavior?

Y Cao, A Chen, RL Jones, J Radcliffe, KL Caldwell… - Neurotoxicology, 2010 - Elsevier
Because the toxicological effects of mercury (Hg) are more serious in the developing central
nervous system of children than adults, there are growing concerns about prenatal and early …

Methylmercury increases glutamate release from brain synaptosomes and glutamate uptake by cortical slices from suckling rat pups: modulatory effect of ebselen

M Farina, KCS Dahm, FD Schwalm… - Toxicological …, 2003 - academic.oup.com
During the early postnatal period the brain is extremely sensitive to external agents. Here,
we examined the effect of subcutaneous injections of methylmercury (MeHg; 2 mg/kg) during …

Unravelling motor behaviour hallmarks in intoxicated adolescents: methylmercury subtoxic-dose exposure and binge ethanol intake paradigm in rats

AN Oliveira, AM Pinheiro, IJA Belém-Filho… - … Science and Pollution …, 2018 - Springer
Methylmercury (MeHg) is a hazardous environmental pollutant, affecting Amazon basin
communities by anthropogenic activities. The exact safe level of MeHg exposure is unclear …

Neurotoxicological effects of low-dose methylmercury and mercuric chloride in developing offspring mice

CF Huang, SH Liu, CJ Hsu, SY Lin-Shiau - Toxicology Letters, 2011 - Elsevier
Mercury is a well-known toxic metal and potently induces severe neurotoxicological effects,
especially in infants and children. The purpose of this study was to explore the underlying …

Considerations on methylmercury (MeHg) treatments in in vitro studies

M Aschner - Neurotoxicology, 2012 - ncbi.nlm.nih.gov
It is quite often that as researchers performing in vitro studies we are asked by reviewers of a
manuscript or a grant proposal “what is the physiological relevance of the concentrations …