Changes in whole blood DNA methylation levels at several CpG sites have been associated
with circulating blood lipids, specifically high-density lipoprotein and triglycerides. This study …

Lipoprotein (a)[Lp (a)] is a major cardiovascular risk factor, which is largely genetically
determined by one major gene locus, the LPA gene. Many aspects of the transcriptional …

Background DNA methylation is a key epigenetic mechanism that is suggested to be
associated with blood lipid levels. We aimed to identify CpG sites at which DNA methylation …

BACKGROUND: Recent findings suggest that DNA methylation, a well-known epigenetic
mechanism, is involved in high-density lipoprotein cholesterol (HDL-C) metabolism and …

Objective—The function of high-density lipoproteins (HDLs) may better reflect their
atheroprotective role, compared with HDL-cholesterol levels. The association between DNA …

Here we examine the association between DNA methylation in circulating leukocytes and
blood lipids in a multi-ethnic sample of 16,265 subjects. We identify 148, 35, and 4 novel …

Lipid traits (total, low-density and high-density lipoprotein cholesterol, and triglycerides) are
risk factors for cardiovascular disease. DNA methylation is not only an inherited but also …

Background—Genome-wide association studies have identified loci influencing circulating
lipid concentrations in humans; further information on novel contributing genes, pathways …

Background—Genetic research regarding blood lipids has largely focused on DNA
sequence variation; few studies have explored epigenetic effects. Genome-wide surveys of …

Although apolipoprotein E (APOE) variants are associated with age‐related diseases, the
underlying mechanism is unknown and DNA methylation may be a potential one. With …