Alteration of the cytoskeleton of mammalian cells cultured in vitro by Clostridium botulinum C2 toxin and C3 ADP-ribosyltransferase.
W Wiegers, I Just, H Müller, A Hellwig… - European journal of …, 1991 - europepmc.org
The effects of Clostridium botulinum C3 ADP-ribosyltransferase and of Clostridium
botulinum C2 toxin were studied on the cytoskeleton of rat hepatoma FAO and human …
botulinum C2 toxin were studied on the cytoskeleton of rat hepatoma FAO and human …
Clostridium botulinum type C produces a novel ADP-ribosyltransferase distinct from botulinum C2 toxin
K Aktories, U Weller, GS Chhatwal - FEBS letters, 1987 - Elsevier
The culture medium of certain strains of Clostridium botulinum type C contains two
separable ADP-ribosyltransferases. Besides the ADP-ribosylation of actin due to botulinum …
separable ADP-ribosyltransferases. Besides the ADP-ribosylation of actin due to botulinum …
ADP-ribosylation of nonmuscle actin with component I of C2 toxin
I Ohishi, S Tsuyama - Biochemical and biophysical research …, 1986 - Elsevier
C 2 toxin elaborated by Clostridium botulinum type C is composed of two dissimilar protein
components, designated components I and II. Component I of the toxin caused ADP …
components, designated components I and II. Component I of the toxin caused ADP …
Botulinum C2 toxin ADP-ribosylates actin and disorganizes the microfilament network in intact cells.
KH Reuner, P Presek, CB Boschek… - European journal of cell …, 1987 - europepmc.org
Botulinum C2 toxin ADP-ribosylates actin in [32P] orthophosphate-labelled intact chick
embryo cells (CEC). The toxin-induced rounding up of CEC is correlated with ADP …
embryo cells (CEC). The toxin-induced rounding up of CEC is correlated with ADP …
Isolation and characterization of a Clostridium botulinum C2 toxin-resistant cell line: evidence for possible involvement of the cellular C2II receptor in growth regulation
G Fritz, P Schroeder, K Aktories - Infection and immunity, 1995 - Am Soc Microbiol
Clostridium botulinum C2 toxin, which consists of the binding component C2II and the
enzyme component C2I, acts on eukaryotic cells by selective ADP-ribosylation of G-actin. To …
enzyme component C2I, acts on eukaryotic cells by selective ADP-ribosylation of G-actin. To …
ADP-Ribosylation of Actin by the Clostridium botulinum C2 Toxin in Mammalian Cells Results in Delayed Caspase-Dependent Apoptotic Cell Death
K Heine, S Pust, S Enzenmüller… - Infection and immunity, 2008 - Am Soc Microbiol
The binary C2 toxin from Clostridium botulinum mono-ADP-ribosylates G-actin in the cytosol
of eukaryotic cells. This modification leads to depolymerization of actin filaments …
of eukaryotic cells. This modification leads to depolymerization of actin filaments …
Clostridium spiroforme toxin is a binary toxin which ADP-ribosylates cellular actin
MR Popoff, P Boquet - Biochemical and biophysical research …, 1988 - Elsevier
We have purified from Clostridium spiroforme strain 246 an heterogenous population of
proteins (S a) ranging from 43 to 47 kilodaltons exhibiting ADP-ribosyl transferase activity as …
proteins (S a) ranging from 43 to 47 kilodaltons exhibiting ADP-ribosyl transferase activity as …
Molecular basis for the pharmacological actions of Clostridium botulinum type C2 toxin.
LL Simpson - Journal of Pharmacology and Experimental …, 1984 - ASPET
The light chain of type C2 toxin produced by Clostridium botulinum was isolated by high-
performance liquid chromatography. The protein eluted as a single peak; as judged by …
performance liquid chromatography. The protein eluted as a single peak; as judged by …
ADP-ribosylation of specific membrane proteins in pheochromocytoma and primary-cultured brain cells by botulinum neurotoxins type C and D
I Matsuoka, B Syuto, K Kurihara, S Kubo - FEBS letters, 1987 - Elsevier
Type C 1 and D toxins produced by Clostridium botulinum caused ADP-ribosylation of a
protein of 24 kDa in membrane preparations of rat clonal pheochromocytoma cells (PC12) …
protein of 24 kDa in membrane preparations of rat clonal pheochromocytoma cells (PC12) …
Clostridial ADP-ribosylating toxins: effects on ATP and GTP-binding proteins
K Aktories - Molecular and cellular biochemistry, 1994 - Springer
The actin cytoskeleton appears to be as the cellular target of various clostridial ADP-
ribosyltransferases which have been described during recent years. Clostridium botulinum …
ribosyltransferases which have been described during recent years. Clostridium botulinum …