Aptamers are single-stranded oligonucleotides that fold into well-defined three-dimensional
shapes, allowing them to bind their targets with high affinity and specificity. They can be …

Introduction: Aptamers are oligonucleotide molecules raised in vitro from large combinatorial
libraries of nucleic acids and developed to bind to targets with high affinity and specificity …

Coined three decades ago, the term aptamer and directed evolution have now reached their
maturity. The concept that nucleic acid could modulate the activity of target protein as ligand …

Nucleic acid-based aptamers have been shown as high-affinity ligands and potential
antagonists of disease-associated proteins. Aptamers, isolated from combinatorial libraries …

Aptamers are small, single-stranded oligonucleotides (DNA or RNA) that bind to their target
with high specificity and affinity. Although aptamers are analogous to antibodies for a wide …

Aptamers are short single-stranded DNA or RNA oligonucleotides that are capable of
binding small molecules, proteins, or nucleotides with high specificity. They show a stable …

Nucleic acid aptamers can be selected from pools of random-sequence oligonucleotides to
bind a wide range of biomedically relevant proteins with affinities and specificities that are …

Aptamers are short single-stranded oligonucleotides that fold into well defined three-
dimensional shapes allowing them to bind to and inhibit their targets with high affinity and …

Aptamers, simply described as chemical antibodies, are synthetic oligonucleotide ligands or
peptides that can be isolated in vitro against diverse targets including toxins, bacterial and …

Aptamers emerged over 20 years ago as a class of nucleic acids able to recognize specific
targets. Today, aptamer-related studies constitute a large and important field of …