[HTML][HTML] Challenges to success in heart failure: cardiac cell therapies in patients with heart diseases

H Oh, H Ito, S Sano - Journal of cardiology, 2016 - Elsevier
Heart failure remains the leading cause of death worldwide, and is a burgeoning problem in
public health due to the limited capacity of postnatal hearts to self-renew. The …

Concise review: heart regeneration and the role of cardiac stem cells

S Koudstaal, SJ Jansen of Lorkeers… - Stem cells …, 2013 - academic.oup.com
Acute myocardial infarction leads to irreversible loss of cardiac myocytes, thereby
diminishing the pump function of the heart. As a result, the strenuous workload imposed on …

Stem cells in regenerative cardiology

S Arbatlı, GS Aslan, F Kocabaş - … Medicine, Volume 1: Stem Cells in …, 2018 - Springer
The common prevalence of heart failure and limitations in its treatment are leading cause of
attention and interest towards the induction of cardiac regeneration with novel approaches …

Stem cells for heart cell therapies

D Jing, A Parikh, JM Canty Jr… - Tissue Engineering Part …, 2008 - liebertpub.com
Myocardial infarction–induced heart failure is a prevailing cause of death in the United
States and most developed countries. The cardiac tissue has extremely limited regenerative …

[HTML][HTML] Cardiac stem cells for myocardial regeneration: they are not alone

YY Leong, WH Ng, GM Ellison-Hughes… - Frontiers in …, 2017 - frontiersin.org
Heart failure is the number one killer worldwide with~ 50% of patients dying within 5 years of
prognosis. The discovery of stem cells, which are capable of repairing the damaged portion …

Innovation in basic science: stem cells and their role in the treatment of paediatric cardiac failure–opportunities and challenges

S Kaushal, JP Jacobs, JG Gossett, A Steele… - Cardiology in the …, 2009 - cambridge.org
Heart failure is a leading cause of death worldwide. Current therapies only delay
progression of the cardiac disease or replace the diseased heart with cardiac …

Stem cells from in-or outside of the heart: isolation, characterization, and potential for myocardial tissue regeneration

WA Noort, JPG Sluijter, MJ Goumans… - Pediatric …, 2009 - Springer
Heart failure emerges with a net loss of viable cardiomyocytes, and there is no current
therapy to reverse this process to improve long-term cardiac function. Due to a change in …

Cardiac progenitor cells and their therapeutic application for cardiac repair

L Cyganek, S Chen, T Borchert, K Guan - 2013 - publications.goettingen-research …
Heart disease is the principal cause of death in humans. Stem cell-based therapy for heart
regeneration has long been seen as a potential application since the heart lacks adequate …

Cardiac cell therapies: the next generation

YH Choi, T Saric, B Nasseri, S Hühn… - Cardiovascular …, 2011 - Wiley Online Library
Although significant advances have been made in terms of pharmacological, catheter‐
based, and surgical palliation, heart failure remains a fatal disease. As a curative concept …

Cardiac-derived stem cell-based therapy for heart failure: progress and clinical applications

YL Tang, YJ Wang, LJ Chen, YH Pan… - Experimental …, 2013 - journals.sagepub.com
Stem cell-based therapy is emerging as a promising strategy to treat end-stage heart failure,
a leading cause of morbidity and mortality. Stem cells can be isolated from a variety of …