G-protein-coupled inwardly rectifying potassium (GIRK) channels contribute to the resting
membrane potential of many neurons, including dopamine (DA) neurons in the ventral …

G protein-gated inwardly rectifying potassium (GIRK) channels are important inhibitory
regulators of neuronal excitability in central nervous system, and the impairment of GIRK …

Southern blot analysis of RT-PCR products from brain and heart revealed multiple products
for a C-terminal region of Kir3. 1. Sequencing yielded clones for wild-type Kir3. 1 and three …

We have cloned by homology screening from a rat brain cDNA library a GIRK3-type (Kir 3.3)
inwardly rectifying K+ channel subunit with high structural similarity to other subfamily …

A mutation in the G-protein-linked inwardly rectifying K+ channel 2 gene (Girk2) is the cause
of theweavermouse phenotype. We determined that the originally publishedGirk2transcript …

The inwardly rectifying K+ channels of the GIRK (Kir3) family, members of the superfamily of
inwardly rectifying K+ channels (Kir), are important physiological tools to regulate excitability …

IT has been suggested that a mutation in a G-proteingated inward rectifier K+ channel
(GIRK2) is responsible for inducing cell death in the cerebellum of homozygous weaver …

G protein-gated inwardly rectifying potassium (GIRK; Kir3) channels, which are members of
the large family of inwardly rectifying potassium channels (Kir1–Kir7), regulate excitability in …

Synaptic cleft acidification occurs following vesicle release. Such a pH change may affect
synaptic transmissions in which G-protein-coupled inward rectifier K+(GIRK) channels play a …

We have developed the first potent, subtype-selective small molecule activator of a G-protein
activated inward-rectifying potassium (GIRK) channel. ML297 is potent (EC50= 160 nM) and …