Efficacy and safety of adding clopidogrel to aspirin on stroke prevention among high vascular risk patients: a meta-analysis of randomized controlled trials

S Chen, Q Shen, Y Tang, L He, Y Li, H Li, M Li, Y Peng - Plos one, 2014 - journals.plos.org
Objectives Whether clopidogrel should be added to aspirin for stroke prevention remained
controversial for the risk of hemorrhagic complications. This meta-analysis was aimed to …

Clopidogrel and aspirin versus aspirin alone for stroke prevention: a meta-analysis

S Tan, X Xiao, H Ma, Z Zhang, J Chen, L Ding, S Yu… - PLoS …, 2015 - journals.plos.org
Background and Purpose Antiplatelet therapy is widely used for the primary or secondary
prevention of stroke. Drugs like clopidogrel have emerged as alternatives for traditional …

Effect of addition of clopidogrel to aspirin on stroke incidence: meta-analysis of randomized trials

S Palacio, RG Hart, LA Pearce… - … Journal of Stroke, 2015 - journals.sagepub.com
Background It remains controversial whether dual antiplatelet therapy reduces stroke more
than aspirin alone. Aim We aimed to assess the effects of adding clopidogrel to aspirin on …

Safety of clopidogrel and aspirin for stroke prevention: implications of the CHARISMA trial

S Ruland - Drug safety, 2008 - Springer
Antiplatelet therapy is universally recommended for the prevention of recurrent events in
patients with noncardioembolic ischaemic stroke or transient ischaemic attack (TIA), acute …

Comparison between aspirin and clopidogrel in secondary stroke prevention based on real‐world data

NF Chi, CP Wen, CH Liu, JY Li, JS Jeng… - Journal of the …, 2018 - Am Heart Assoc
Background Clopidogrel was thought to be superior to aspirin for secondary prevention of
vascular diseases in clinical trials. In this study we assessed the safety and efficacy of …

Combination antiplatelet therapy for secondary stroke prevention: enhanced efficacy or double trouble?

MHU Usman, LA Notaro, R Nagarakanti… - The American journal of …, 2009 - Elsevier
The evaluation of antithrombotic agents for secondary stroke prevention has focused on
stroke reduction. The aim of this analysis was to focus specifically on the increase in …

Aspirin and clopidogrel compared with clopidogrel alone after recent ischaemic stroke or transient ischaemic attack in high-risk patients (MATCH): randomised, double …

HC Diener, J Bogousslavsky, LM Brass, C Cimminiello… - The Lancet, 2004 - thelancet.com
Background Clopidogrel was superior to aspirin in patients with previous manifestations of
atherothrombotic disease in the CAPRIE study and its benefit was amplified in some high …

Aspirin plus clopidogrel as secondary prevention after stroke or transient ischemic attack: a systematic review and meta-analysis

Q Zhang, C Wang, M Zheng, Y Li, J Li, L Zhang… - Cerebrovascular …, 2015 - karger.com
Background: Antiplatelet agents are the mainstay for secondary prevention of non-
cardioembolic stroke. This systematic review examined the safety and efficacy of short …

Benefits and risks of clopidogrel vs. aspirin monotherapy after recent ischemic stroke: a systematic review and meta‐analysis

M Paciaroni, B Ince, B Hu, JS Jeng… - Cardiovascular …, 2019 - Wiley Online Library
Aim. Though combination of clopidogrel added to aspirin has been compared to aspirin
alone in patients with stroke or transient ischemic attack, limited data exists on the relative …

Aspirin better than clopidogrel on major adverse cardiovascular events reduction after ischemic stroke: a retrospective nationwide cohort study

AN Vidyanti, L Chan, CL Lin, CH Muo, CY Hsu… - PLoS …, 2019 - journals.plos.org
Background Several clinical trials reported that clopidogrel was superior to aspirin in
secondary stroke prevention by reducing the risk of major adverse cardiovascular events …