Introduction: Infection is the leading cause of complications in critically ill, and its presence
significantly influences the treatment outcome. Empirical antibiotic therapy (EAT) is justified if …

Methods: A prospective observational prevalence study was conducted over a 3-day period.
Demographic, physiologic, and bacteriologic data were collected for each patient. The …

Nine hundred ninety-eight adult patients admitted to intensive care units (ICUs) in the United
States over a 24-hour period in 2011 were studied. Prolonged empiric antibiotic therapy …

Patients with complex medical and surgical issues are often admitted to the intensive care
unit (ICU). In such patients, prompt administration of broad spectrum empirical antibiotics is …

Introduction. Most patients admitted to the Intensive Care Units (ICU) receive antimicrobial
treatment. A proper therapeutic strategy may be useful in decreasing inappropriate empirical …

Objective: The purpose of this study is to determine the rate of prolonged empiric antibiotic
therapy in adult ICUs in the United States. Our secondary objective is to examine the …

Empiric antibiotic therapy—the administration of antibiotics before a microbiological
diagnosis of infection is established—is a widely-used, but unproven practice in …

Background: It is widely acknowledged that the presence of infection is an important
outcome determinant for intensive care unit (ICU) patients. In fact, antibiotics are one of the …

Abstract Background: In Vietnam, a number of recent epidemiological studies demonstrated
that the prevalence of antibiotic-resistant bacteria has been rapidly increasing, especially in …

The appropriate antibiotic treatment of patients with bacterial sepsis in the intensive care unit
(ICU) remains a challenge. Considering that current international guidelines recommend 7 …