Importance Therapeutic hypothermia reduces risk of death and disability in infants with
moderate to severe hypoxic ischemic encephalopathy (HIE). Randomized clinical trials of …

Context: Therapeutic hypothermia is the recommended treatment for neonates with
moderate or severe hypoxic ischemic encephalopathy (HIE). There is an increasing trend to …

Aims Hypoxic ischaemic encephalopathy (HIE) remains a significant cause of long term
neurodisability despite therapeutic hypothermia (TH). Infants with mild HIE, representing …

Importance Hypothermia initiated at less than 6 hours after birth reduces death or disability
for infants with hypoxic-ischemic encephalopathy at 36 weeks' or later gestation. To our …

Objective To establish the evidence of therapeutic hypothermia for newborns with hypoxic
ischemic encephalopathy (HIE). Data Sources Cochrane Central Register of Controlled …

Objective Hypoxic-ischaemic encephalopathy (HIE) remains a leading cause of neonatal
mortality and neurodisability. We aimed to determine the incidence of HIE and management …

Background Therapeutic hypothermia reduces the risk of death, or moderate to severe
neurodevelopmental impairment (NDI) in term infants with hypoxic-ischemic …

Background We previously reported early results of a randomized trial of whole-body
hypothermia for neonatal hypoxic–ischemic encephalopathy showing a significant reduction …

Importance Hypothermia for 72 hours at 33.5° C for neonatal hypoxic-ischemic
encephalopathy reduces death or disability, but rates continue to be high. Objective To …

Background and Objective: There remains an unmet clinical need for markers that predict
outcomes in the hypothermia-treated (HT) infants with HIE. The aim of this meta-analysis …