Importance Latent tuberculosis infection (LTBI) can progress to active tuberculosis disease,
causing morbidity and mortality. Objective To review the evidence on benefits and harms of …

Importance Five to ten percent of individuals with latent tuberculosis infection (LTBI)
progress to active tuberculosis (TB) disease. Identifying and treating LTBI is a key …

Importance In the US, tuberculosis remains an important preventable disease, including
active tuberculosis, which may be infectious, and latent tuberculosis infection (LTBI), which …

Importance Tuberculosis remains an important preventable disease in the United States. An
effective strategy for reducing the transmission, morbidity, and mortality of active disease is …

IMPORTANCE Tuberculosis remains an important preventable disease in the United States.
An effective strategy for reducing the transmission, morbidity, and mortality of active disease …

Background Treatment of latent tuberculosis infection is an important strategy to prevent
tuberculosis disease. In the USA, three tests are used to identify latent tuberculosis infection …

Objective Immunosuppressed individuals are at a high risk of latent tuberculosis infection
(LTBI) and clinical practice guidelines for the screening and management of LTBI in at-risk …

Background Use of an interferon-γ (IFN-γ) release assay or tuberculin skin test for detection
and management of latent tuberculosis infection is controversial. For both types of test, we …

Background: Until recently, the tuberculin skin test was the only test for detecting latent
tuberculosis (TB) infection, but 2 ex vivo interferon-γ release assays (IGRAs) are now …

Rationale: To improve the effectiveness of tuberculosis (TB) control programs in the United
States by identifying cost-effective priorities for screening for latent tuberculosis infection …