Extracellular Vesicle-Based SARS-CoV-2 Vaccine

Y Matsuzaka, R Yashiro - Vaccines, 2023 - mdpi.com
Messenger ribonucleic acid (RNA) vaccines are mainly used as SARS-CoV-2 vaccines.
Despite several issues concerning storage, stability, effective period, and side effects, viral …

Promising extracellular vesicle-based vaccines against viruses, including SARS-CoV-2

B Sabanovic, F Piva, M Cecati, M Giulietti - Biology, 2021 - mdpi.com
Simple Summary Extracellular vesicles (EVs) allow cell-to-cell communication and can
induce a strong immune response, by presenting antigens. EVs can be engineered to …

Exosome-based COVID-19 vaccine

J Kim, N Thapa - Cell-Secreted Vesicles: Methods and Protocols, 2023 - Springer
Extracellular vesicles (EVs) enable cell-to-cell communication and, by delivering antigens,
can stimulate the immune response strongly. Approved in use SARS-CoV-2 vaccine …

Extracellular vesicle-based vaccine platform displaying native viral envelope proteins elicits a robust anti-SARS-CoV-2 response in mice

K Polak, N Greze, M Lachat, D Merle, S Chiumento… - BioRxiv, 2020 - biorxiv.org
Extracellular vesicles (EVs) emerge as essential mediators of intercellular communication.
DNA vaccines encoding antigens presented on EVs efficiently induce T-cell responses and …

Update on extracellular vesicle-based vaccines and therapeutics to combat COVID-19

T Mustajab, MS Kwamboka, DA Choi, DW Kang… - International Journal of …, 2022 - mdpi.com
The COVID-19 pandemic has had a deep impact on people worldwide since late 2019 when
SARS-CoV-2 was first identified in Wuhan, China. In addition to its effect on public health, it …

SARS-CoV-2 antigen-carrying extracellular vesicles activate T cell responses in a human immunogenicity model

SE Cummings, SP Delaney, FSD Bissonnette… - Iscience, 2024 - cell.com
Extracellular vesicles (EVs) are entering the clinical arena as novel biologics for infectious
diseases, potentially serving as the immunogenic components of next generation vaccines …

Meet changes with constancy: Defence, antagonism, recovery, and immunity roles of extracellular vesicles in confronting SARS‐CoV‐2

X Chen, H Li, H Song, J Wang, X Zhang… - Journal of …, 2022 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS‐CoV‐2), has wrought havoc on the world economy and …

An intranasal vaccine based on outer membrane vesicles against SARS-CoV-2

HB Thapa, AM Müller, A Camilli, S Schild - Frontiers in Microbiology, 2021 - frontiersin.org
The prevailing pandemic of SARS-CoV-2 highlights the desperate need of alternative
vaccine-platforms, which are safe, effective, and can be modified to carry antigens of …

A Review of Extracellular Vesicles in COVID‐19 Diagnosis, Treatment, and Prevention

P Su, Y Wu, F Xie, Q Zheng, L Chen, Z Liu… - Advanced …, 2023 - Wiley Online Library
The 2019 novel coronavirus disease (COVID‐19) pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is ongoing, and has necessitated …

Extracellular vesicles in COVID-19 prognosis, treatment, and vaccination: An update

A Hernández-Díazcouder, C Díaz-Godínez… - Applied Microbiology …, 2023 - Springer
The lethality of the COVID 19 pandemic became the trigger for one of the most meteoric
races on record in the search for strategies of disease control. Those include development of …