Prognostic Significance of TERT Promoter Mutations in Papillary Thyroid Carcinomas in a BRAFV600E Mutation–Prevalent Population

SE Lee, TS Hwang, YL Choi, HS Han, WS Kim… - Thyroid, 2016 - liebertpub.com
Background: The role of telomerase reverse transcriptase (TERT) promoter mutations in
differentiated thyroid cancer has been well established. These mutations have a significantly …

Clinicopathological indicators for TERT promoter mutation in papillary thyroid carcinoma

HY Na, HW Yu, W Kim, JH Moon, CH Ahn… - Clinical …, 2022 - Wiley Online Library
Objective Mutations in the telomerase reverse transcriptase (TERT) promoter have been
reported as a convincing prognostic factor in papillary thyroid carcinomas (PTCs). We aimed …

TERT promoter and BRAF V600E mutations in papillary thyroid cancer: a single-institution experience in Korea

MJ Kim, JK Kim, GJ Kim, SW Kang, J Lee, JJ Jeong… - Cancers, 2022 - mdpi.com
Simple Summary TERT promoter mutation has recently emerged as a promising prognostic
biomarker for aggressive papillary thyroid cancer (PTC), along with BRAF B600E mutation …

BRAF V600E and TERT promoter mutations in papillary thyroid carcinoma in Chinese patients

J Sun, J Zhang, J Lu, J Gao, X Ren, L Teng, H Duan… - PLoS …, 2016 - journals.plos.org
Background The BRAF V600E and telomerase reverse transcriptase (TERT) promoter
mutations have been reported in papillary thyroid carcinoma (PTC). The aim of this …

[HTML][HTML] BRAF and TERT promoter mutations in the aggressiveness of papillary thyroid carcinoma: a study of 653 patients

L Jin, E Chen, S Dong, Y Cai, X Zhang, Y Zhou… - Oncotarget, 2016 - ncbi.nlm.nih.gov
The role of telomerase reverse transcriptase (TERT) gene promoter mutations in the
aggressiveness of papillary thyroid cancer (PTC) remains to be further investigated. Here we …

[HTML][HTML] Highly prevalent BRAF V600E and low-frequency TERT promoter mutations underlie papillary thyroid carcinoma in Koreans

SY Kim, T Kim, K Kim, JS Bae… - Journal of Pathology …, 2020 - synapse.koreamed.org
Background The presence of telomerase reverse transcriptase (TERT) promoter mutations
have been associated with a poor prognosis in patients with papillary thyroid carcinomas …

Coexistence of TERT Promoter Mutations and the BRAF V600E Alteration and Its Impact on Histopathological Features of Papillary Thyroid Carcinoma in a Selected …

D Rusinek, A Pfeifer, J Krajewska… - International Journal of …, 2018 - mdpi.com
TERT promoter (TERT p) mutations are important factors in papillary thyroid carcinomas
(PTCs). They are associated with tumor aggressiveness, recurrence, and disease-specific …

[PDF][PDF] TERT promoter mutations and long-term survival in patients with thyroid cancer

TH Kim, YE Kim, S Ahn, JY Kim, CS Ki… - Endocr Relat …, 2016 - scholar.archive.org
TERT promoter mutations are emerging prognostic biomarkers in multiple cancers and are
found in highly aggressive thyroid cancer. Our aim is to investigate the prognostic value of …

TERT Promoter Mutations and Their Association with BRAF V600E Mutation and Aggressive Clinicopathological Characteristics of Thyroid Cancer

X Liu, S Qu, R Liu, C Sheng, X Shi, G Zhu… - The Journal of …, 2014 - academic.oup.com
Context: Promoter mutations chr5: 1,295,228 C> T and chr5: 1,295,250 C> T (termed C228T
and C250T, respectively) in the gene for telomerase reverse transcriptase (TERT) have …

Prognostic effects of TERT promoter mutations are enhanced by coexistence with BRAF or RAS mutations and strengthen the risk prediction by the ATA or TNM …

YS Song, JA Lim, H Choi, JK Won, JH Moon, SW Cho… - Cancer, 2016 - Wiley Online Library
BACKGROUND Recent reports suggest that mutations in the promoter of the gene encoding
telomerase reverse transcriptase (TERT) affect thyroid cancer outcomes. METHODS In all …