[HTML][HTML] Multi-trait analysis for genome-wide association study of five psychiatric disorders
We conducted a cross-trait meta-analysis of genome-wide association study on
schizophrenia (SCZ)(n= 65,967), bipolar disorder (BD)(n= 41,653), autism spectrum …
schizophrenia (SCZ)(n= 65,967), bipolar disorder (BD)(n= 41,653), autism spectrum …
Identifying common genome-wide risk genes for major psychiatric traits
Major psychiatric traits are genetically inter-correlated with one another, but it not well known
which genes play pleiotropic effects across different traits. We curated and compared genes …
which genes play pleiotropic effects across different traits. We curated and compared genes …
Gene-based analyses reveal novel genetic overlap and allelic heterogeneity across five major psychiatric disorders
Studies using genome-wide association (GWA) single nucleotide polymorphism (SNP) level
data have indicated genetic overlap across the five major disorders in the Psychiatric …
data have indicated genetic overlap across the five major disorders in the Psychiatric …
Common variants conferring risk of schizophrenia: a pathway analysis of GWAS data
Unlike the typical analysis of single markers in genome-wide association studies (GWAS),
we incorporated Gene Set Enrichment Analysis (GSEA) and hypergeometric test and …
we incorporated Gene Set Enrichment Analysis (GSEA) and hypergeometric test and …
[HTML][HTML] Integrative analysis of genome-wide association studies identifies novel loci associated with neuropsychiatric disorders
X Yao, JT Glessner, J Li, X Qi, X Hou, C Zhu… - Translational …, 2021 - nature.com
Neuropsychiatric disorders, such as autism spectrum disorder (ASD), attention deficit
hyperactivity disorder (ADHD), schizophrenia (SCZ), bipolar disorder (BIP), and major …
hyperactivity disorder (ADHD), schizophrenia (SCZ), bipolar disorder (BIP), and major …
Dimensional and transdiagnostic phenotypes in psychiatric genome-wide association studies
Genome-wide association studies (GWAS) provide biological insights into disease onset
and progression and have potential to produce clinically useful biomarkers. A growing body …
and progression and have potential to produce clinically useful biomarkers. A growing body …
A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder
KS Wang, XF Liu, N Aragam - Schizophrenia research, 2010 - Elsevier
Schizophrenia and bipolar disorder both have strong inherited components. Recent studies
have indicated that schizophrenia and bipolar disorder may share more than half of their …
have indicated that schizophrenia and bipolar disorder may share more than half of their …
Genome-wide association study detected novel susceptibility genes for schizophrenia and shared trans-populations/diseases genetic effect
M Ikeda, A Takahashi, Y Kamatani… - Schizophrenia …, 2019 - academic.oup.com
Genome-wide association studies (GWASs) have identified> 100 susceptibility loci for
schizophrenia (SCZ) and demonstrated that SCZ is a polygenic disorder determined by …
schizophrenia (SCZ) and demonstrated that SCZ is a polygenic disorder determined by …
Genome‐Wide Findings in Schizophrenia and the Role of Gene–Environment Interplay
R Van Winkel, G Esquivel, G Kenis… - CNS neuroscience & …, 2010 - Wiley Online Library
The recent advent of genome‐wide mass‐marker technology has resulted in renewed
optimism to unravel the genetic architecture of psychotic disorders. Genome‐wide …
optimism to unravel the genetic architecture of psychotic disorders. Genome‐wide …
Genome-wide significant associations in schizophrenia to ITIH3/4, CACNA1C and SDCCAG8, and extensive replication of associations reported by the Schizophrenia …
ML Hamshere, JTR Walters, R Smith, AL Richards… - Molecular …, 2013 - nature.com
Abstract The Schizophrenia Psychiatric Genome-Wide Association Study Consortium (PGC)
highlighted 81 single-nucleotide polymorphisms (SNPs) with moderate evidence for …
highlighted 81 single-nucleotide polymorphisms (SNPs) with moderate evidence for …