Neuropeptides are a complex set of messenger molecules controlling a wide array of
regulatory functions and behaviors within an organism. These neuromodulators are cleaved …

Due to their involvement in numerous biochemical pathways, neuropeptides have been the
focus of many recent research studies. Unfortunately, classic analytical methods, such as …

This review focuses on the contributions of modern mass spectrometry to neuropeptide
research. An introduction to newer mass spectrometric techniques is provided. Also, the use …

Neuropeptides are an important class of signaling molecules in the nervous and
neuroendocrine system, but they are challenging to study due to their low concentration in …

Neuropeptides are an important class of endogenous peptides in the nervous system that
regulate physiological functions such as feeding, glucose homeostasis, pain, memory …

Neuropeptides are important mediators in the functionality of the brain and other
neurological organs. Because neuropeptides exist in a wide range of concentrations …

The lobster Homarus americanus has long served as an important animal model for
electrophysiological and behavioral studies. Using this model, we performed a …

Imaging mass spectrometry (IMS) of neuropeptides in crustacean neuronal tissues was
performed on a MALDI-TOF/TOF instrument. Sample preparation protocols were developed …

Neuropeptidomics refers to a global characterization approach for the investigation of
neuropeptides, often under specific physiological conditions. Neuropeptides comprise a …

Mass spectrometry-based neuropeptidomics is one of the most powerful approaches for
identification of endogenous neuropeptides in the brain. Until now, however, the …