The neural basis of functional brain imaging signals

D Attwell, C Iadecola - Trends in neurosciences, 2002 - Elsevier
The haemodynamic responses to neural activity that underlie the blood-oxygen-level-
dependent (BOLD) signal used in functional magnetic resonance imaging (fMRI) of the brain …

The underpinnings of the BOLD functional magnetic resonance imaging signal

NK Logothetis - Journal of Neuroscience, 2003 - Soc Neuroscience
The good coverage and high resolution afforded by functional magnetic resonance imaging
(fMRI) make it an excellent tool for the noninvasive imaging of the human brain. Equally …

The neural basis of the blood–oxygen–level–dependent functional magnetic resonance imaging signal

NK Logothetis - … Transactions of the Royal Society of …, 2002 - royalsocietypublishing.org
Magnetic resonance imaging (MRI) has rapidly become an important tool in clinical
medicine and biological research. Its functional variant (functional magnetic resonance …

On the nature of the BOLD fMRI contrast mechanism

NK Logothetis, J Pfeuffer - Magnetic resonance imaging, 2004 - Elsevier
Since its development about 15 years ago, functional magnetic resonance imaging (fMRI)
has become the leading research tool for mapping brain activity. The technique works by …

Quantitative functional MRI: concepts, issues and future challenges

GB Pike - Neuroimage, 2012 - Elsevier
Since its inception 20years ago, functional magnetic resonance imaging (fMRI) of the human
brain based on the blood oxygenation level dependent (BOLD) contrast phenomenon has …

Brain function and neurophysiological correlates of signals used in functional neuroimaging

M Lauritzen, L Gold - Journal of Neuroscience, 2003 - Soc Neuroscience
Over the last 30 years the development of new and exciting techniques has enabled us to
observe the localization of function in the human brain and to discover how the working …

The role of neuronal signaling in controlling cerebral blood flow

CT Drake, C Iadecola - Brain and language, 2007 - Elsevier
Well-regulated blood flow within the brain is vital to normal function. The brain's requirement
for sufficient blood flow is ensured by a tight link between neural activity and blood flow. The …

Linear coupling between functional magnetic resonance imaging and evoked potential amplitude in human somatosensory cortex

OJ Arthurs, EJ Williams, TA Carpenter, JD Pickard… - Neuroscience, 2000 - Elsevier
The interpretation of task-induced functional imaging of the brain is critically dependent on
understanding the relationship between observed blood flow responses and the underlying …

[PDF][PDF] Biophysical and physiological origins of blood oxygenation level-dependent fMRI signals

SG Kim, S Ogawa - Journal of Cerebral Blood Flow & …, 2012 - journals.sagepub.com
After its discovery in 1990, blood oxygenation level-dependent (BOLD) contrast in functional
magnetic resonance imaging (fMRI) has been widely used to map brain activation in …

Interpreting the BOLD signal

NK Logothetis, BA Wandell - Annu. Rev. Physiol., 2004 - annualreviews.org
▪ Abstract The development of functional magnetic resonance imaging (fMRI) has brought
together a broad community of scientists interested in measuring the neural basis of the …