The neural basis of functional brain imaging signals

D Attwell, C Iadecola - Trends in neurosciences, 2002 - cell.com
The haemodynamic responses to neural activity that underlie the blood-oxygen-level-
dependent (BOLD) signal used in functional magnetic resonance imaging (fMRI) of the brain …

The neural basis of the blood–oxygen–level–dependent functional magnetic resonance imaging signal

NK Logothetis - … Transactions of the Royal Society of …, 2002 - royalsocietypublishing.org
Magnetic resonance imaging (MRI) has rapidly become an important tool in clinical
medicine and biological research. Its functional variant (functional magnetic resonance …

Brain function and neurophysiological correlates of signals used in functional neuroimaging

M Lauritzen, L Gold - Journal of Neuroscience, 2003 - Soc Neuroscience
Over the last 30 years the development of new and exciting techniques has enabled us to
observe the localization of function in the human brain and to discover how the working …

The underpinnings of the BOLD functional magnetic resonance imaging signal

NK Logothetis - Journal of Neuroscience, 2003 - Soc Neuroscience
The good coverage and high resolution afforded by functional magnetic resonance imaging
(fMRI) make it an excellent tool for the noninvasive imaging of the human brain. Equally …

The role of neuronal signaling in controlling cerebral blood flow

CT Drake, C Iadecola - Brain and language, 2007 - Elsevier
Well-regulated blood flow within the brain is vital to normal function. The brain's requirement
for sufficient blood flow is ensured by a tight link between neural activity and blood flow. The …

Linear coupling between functional magnetic resonance imaging and evoked potential amplitude in human somatosensory cortex

OJ Arthurs, EJ Williams, TA Carpenter, JD Pickard… - Neuroscience, 2000 - Elsevier
The interpretation of task-induced functional imaging of the brain is critically dependent on
understanding the relationship between observed blood flow responses and the underlying …

Investigating neural–hemodynamic coupling and the hemodynamic response function in the awake rat

C Martin, J Martindale, J Berwick, J Mayhew - Neuroimage, 2006 - Elsevier
An understanding of the relationship between changes in neural activity and the
accompanying hemodynamic response is crucial for accurate interpretation of functional …

Quantitative functional MRI: concepts, issues and future challenges

GB Pike - Neuroimage, 2012 - Elsevier
Since its inception 20years ago, functional magnetic resonance imaging (fMRI) of the human
brain based on the blood oxygenation level dependent (BOLD) contrast phenomenon has …

How and when the fMRI BOLD signal relates to underlying neural activity: the danger in dissociation

A Ekstrom - Brain research reviews, 2010 - Elsevier
Functional magnetic resonance imaging (fMRI) has become the dominant means of
measuring behavior-related neural activity in the human brain. Yet the relation between the …

The physics of functional magnetic resonance imaging (fMRI)

RB Buxton - Reports on Progress in Physics, 2013 - iopscience.iop.org
Functional magnetic resonance imaging (fMRI) is a methodology for detecting dynamic
patterns of activity in the working human brain. Although the initial discoveries that led to …