[PDF][PDF] Linear modeling of genetic networks from experimental data.

EP van Someren, LFA Wessels, MJT Reinders - Ismb, 2000 - Citeseer
In this paper, the regulatory interactions between genes are modeled by a linear genetic
network that is estimated from gene expression data. The inference of such a genetic …

A comparison of genetic network models

LFA Wessels, EPVAN SOMEREN… - Biocomputing …, 2000 - World Scientific
With the completion of the sequencing of the human genome, the need for tools capable of
unraveling the interaction and functionality of genes becomes extremely urgent. In answer to …

Genetic network models: A comparative study

EP van Someren, LFA Wessels… - MicroArrays: Optical …, 2001 - spiedigitallibrary.org
Currently, the need arises for tools capable of unraveling the functionality of genes based on
the analysis of microarray measurements. Modeling genetic interactions by means of …

Analysis of gene sets based on the underlying regulatory network

A Shojaie, G Michailidis - Journal of Computational Biology, 2009 - liebertpub.com
Networks are often used to represent the interactions among genes and proteins. These
interactions are known to play an important role in vital cell functions and should be included …

Principled computational methods for the validation discovery of genetic regulatory networks

AJ Hartemink - 2001 - dspace.mit.edu
As molecular biology continues to evolve in the direction of high-throughput collection of
data, it has become increasingly necessary to develop computational methods for analyzing …

Development of a system for the inference of large scale genetic networks

Y Maki, D Tominaga, M Okamoto, S Watanabe… - Biocomputing …, 2000 - World Scientific
We propose a system named AIGNET (Algorithms for Inference of Genetic Networks), and
introduce two top-down approaches for the inference of interrelated mechanism among …

Modeling transcriptional control in gene networks—methods, recent results, and future directions

P Smolen, DA Baxter, JH Byrne - Bulletin of mathematical biology, 2000 - Springer
Mathematical models are useful for providing a framework for integrating data and gaining
insights into the static and dynamic behavior of complex biological systems such as …

[PDF][PDF] Simulation studies for the identification of genetic networks from cDNA array and regulatory activity data

DE Zak, FJ Doyle, GE Gonye… - Proceedings of the …, 2001 - researchgate.net
ABSTRACT A model genetic regulatory network for the evaluation of genetic regulatory
network identification methods is described in the present work. This model is novel …

A gene network inference method from continuous-value gene expression data of wild-type and mutants

KM Kyoda, S Onami, M Morohashi, H Kitano - Genome Informatics, 2000 - jstage.jst.go.jp
In this paper we introduce a new inference method of a gene regulatory network from
steadystate gene expression data. Our method determines a regulatory structure consistent …

A duplication growth model of gene expression networks

A Bhan, DJ Galas, TG Dewey - Bioinformatics, 2002 - academic.oup.com
Motivation: There has been considerable interest in developing computational techniques
for inferring genetic regulatory networks from whole-genome expression profiles. When …