The translocation t (8; 21) is one of the most common structural aberrations in acute myeloid
leukemia (AML). Excellent response rates and a better relapse-free survival have been …

Nine acute myelogenous leukemia (AML) patients with a translocation 8; 21, who were
treated at Keio University Hospital between 1983 and August 1990, were reviewed. All of …

8; 21 translocation was found in 10 AML patients. These patients exhibited a distinct clinical
and haematological picture, characterized by M2 bone marrow, with rather good maturation …

A retrospective study of 148 previously untreated patients with acute nonlymphocytic
leukemia (ANLL) presenting at (8; 21) was undertaken by the Groupe Français de …

Clinical and laboratory features of seven patients with acute leukemia associated with the (4;
11) chromosome translocation are presented. Leukemic blasts of these patients showed …

Previous small series have suggested that acute myeloid leukemia with t (8; 16) is a distinct
morphologic and clinical entity associated with poor prognosis. We describe 18 patients with …

Twenty-three patients with de novo acute myeloid leukemia (AML) and t (8; 21)(q22; q22),
including 2 children aged 7 and 14 and 21 adults aged 16 to 68 (median 29), were treated …

The cellular and molecular genetic aberrations of hematopoietic and lymphoid tissues are
increasingly important in leukemia classification and are prognostically significant. Although …

The t (8; 21) abnormality occurs in a minority of acute myeloid leukemia (AML) patients. The
translocation results in an in‐frame fusion of two genes, resulting in a fusion protein of one N …

Abstract The translocation (8; 21)(q22; q22) is commonly associated with acute myeloid
leukemia (AML) M2 according to the French‐American‐British (FAB) classification. We …