We report a patient with acute myeloid leukemia (AML) and t (3; 21; 8)(q21; q22; q22). This
translocation has not been previously described in de novo or relapsed AML. The patient is …

Purpose: This was a retrospective analysis of outcome based on cytogenetics for a
Children's Cancer Group phase 3 trial of acute myelogenous leukemia (AML)(CCG-2891) …

Recurrent chromosomal rearrangements are observed in many leukemia subtypes.
Recently, it has been shown that several of these translocations/inversions were associated …

Translocations involving the EVI1/MDS1 gene at 3q26 and the TEL gene at 12p13 are
comparatively common in acute leukemia, but a translocation between the two genes has …

Analysis of the bone marrow karyotype in 109 consecutive untreated patients with acute
lymphoblastic leukemia (ALL) by the G-banding technique revealed the presence of a …

A three‐way rearrangement involving chromosomes 1, 8, and 21 was observed in bone
marrow cells from a female with acute myeloblastic leukemia, subtype M2 (AML‐M2). The …

This report describes the clinical and laboratory features of seven cases of acute leukemia
associated with the 4; 11 chromosomal translocation. All seven children had acute …

Two patients with acute lymphocytic leukemia are described in whom G-and R-banding
analysis revealed in bone marrow cells a translocation t (4; 11)(q21; q23). The clinical data …

We report the results of cytogenetic, fluorescence in situ hybridization (FISH) and molecular
analyses in a 15-year-old boy diagnosed with acute myeloid leukemia subtype M2 (AML …

Seven cases of acute nonlymphoblastic leukemia showing t (8; 21)(q22; q22) at diagnosis
are described. Involvement of a sex chromosome was found in all patients (in six cases as a …