The high‐affinity glycine transporter in neurons and glial cells is the primary means of
inactivating synaptic glycine. Previous molecular cloning studies have indicated …

Neurotransmitter transport systems are major targets for therapeutic alterations in synaptic
function. We have cloned and sequenced a cDNA encoding the human type 2 glycine …

Glutamate is the primary excitatory neurotransmitter in the mammalian brain. Glutamatergic
neurotransmission may be modulated at multiple levels, only a minority of which are …

A neurotransmitter transporter can potentially mediate uptake or release of substrate, and its
stoichiometry is a key factor that controls the driving force and thus the neurotransmitter flux …

We studied four different cDNAs encoding GABA transporters and three different cDNAs
encoding glycine transporters in mouse and rat brains. A genomic clone of two of the glycine …

Na+/Cl (-)-dependent glycine transporters are crucial for the termination of
neurotransmission at glycinergic synapses. Two different glycine transporter genes, GlyT1 …

High-affinity transporters mediate the removal of released neurotransmitters from synapses,
thereby terminating their synaptic action. A novel glycine transporter has recently been …

In the brain, neurons and glial cells compete for the uptake of the fast neurotransmitters,
glutamate, GABA and glycine, through specific transporters. The relative contributions of glia …