110 Delayed remodelling in severe LVSD, does this reduce the need for primary prevention ICDs? Ideal-HF feasibility study

L Whittaker, M Chapman, R Maier, L Chang, D Austin… - 2024 - heart.bmj.com
Introduction Heart failure with reduced ejection fraction (HFrEF) increases the risk of sudden
cardiac death (SCD). ESC and NICE guidelines recommend primary prevention implantable …

The optimal timing of primary prevention implantable cardioverter-defibrillator referral in the rapidly changing medical landscape

JA Wong, JD Roberts, JS Healey - Canadian Journal of Cardiology, 2021 - Elsevier
The use of implantable cardioverter-defibrillators (ICDs) significantly reduces the risk of
mortality in patients with heart failure with reduced ejection fraction (HFrEF). Current …

Sudden Cardiac Death With Heart Failure Despite Improvement in LV Ejection Fraction: A Population-Based Study

H Chugh, A Uy-Evanado, AS Sargsyan, H Aziz, J Jui… - Circulation, 2023 - Am Heart Assoc
Introduction: Individuals with heart failure (HF) and severely reduced LVEF (≤ 35%) have
increased risk of SCD and qualify for primary prevention ICD implantation. Guideline …

[HTML][HTML] Waiting Period Prior to ICD Implantation in Newly-Diagnosed HFrEF: A Window of Opportunity

EM DeFilippis, J Butler… - Circulation. Heart failure, 2017 - ncbi.nlm.nih.gov
A critical “waiting period” of~ 3 months is generally accepted in patients with
newlydiagnosed heart failure with reduced ejection fraction (HFrEF) outside the context of …

[HTML][HTML] A risk score to predict the absence of left ventricular reverse remodeling: Implications for the timing of ICD implantation in primary prevention

J Pérez-Rodon, E Galve, C Pérez-Bocanegra… - Journal of …, 2018 - Elsevier
Background A prophylactic implantable cardioverter defibrillator (ICD) in patients with heart
failure and reduced left ventricular ejection fraction (HFrEF) is only indicated when left …

[HTML][HTML] Time to rechallenge primary prevention ICD guidelines

B Wong, K McDonald, D Keane - ESC Heart Failure, 2022 - ncbi.nlm.nih.gov
Patients, therapy, and evidence have evolved in leaps since 2002, when MADIT-2 1 first
demonstrated a mortality benefit from using primary prevention ICD therapy. From 1995 to …

[HTML][HTML] Personalizing Risk Assessment for Sudden Cardiac Death in Heart Failure: A Dream or a Reality?

JE Wilcox, SM Al-Khatib - Heart Failure, 2023 - jacc.org
Left ventricular reverse remodeling (LVRR) in patients with heart failure with reduced
ejection fraction (HFrEF) is a commonly encountered clinical phenomenon after treatment …

Efficacy of primary preventive ICD therapy in an unselected population of patients with reduced left ventricular ejection fraction

J Sjöblom, T Kalm, F Gadler, L Ljung, V Frykman… - EP …, 2014 - academic.oup.com
Aims International guidelines advocate an implantable cardioverter and defibrillator (ICD) in
patients with reduced left ventricular ejection fraction (LVEF) to prevent sudden death (SCD) …

[HTML][HTML] Compliance with Guideline-Directed Medical Therapy and Early Implantable Cardioverter-Defibrillator Activation in Heart Failure: A Retrospective Study

I Prepolec, V Pašara, A Nekić, JE Bogdanić… - Reviews in …, 2024 - imrpress.com
Background: This study was conducted to evaluate compliance with guideline-directed
optimal medical therapy (OMT) and its association with early implantable cardioverter …

Predictors of primary prevention implantable cardioverter‐defibrillator use in heart failure with reduced ejection fraction: impact of the predicted risk of sudden cardiac …

B Schrage, LH Lund, L Benson… - European Journal of …, 2022 - Wiley Online Library
Aims Use of implantable cardioverter‐defibrillators (ICD) for primary prevention of sudden
cardiac death (SCD) in heart failure with reduced ejection fraction (HFrEF) is limited. We …