A lipidomic analysis of placenta in preeclampsia: evidence for lipid storage
In preeclampsia, maternal insulin resistance leads to defective expansion of adipocytes,
enhanced adipocyte lipolysis, up-regulation of very low density lipoprotein synthesis …
enhanced adipocyte lipolysis, up-regulation of very low density lipoprotein synthesis …
[HTML][HTML] Increased placental phospholipid levels in pre-eclamptic pregnancies
X Huang, A Jain, M Baumann, M Körner… - International journal of …, 2013 - mdpi.com
Physiological pregnancy is associated with an increase in lipids from the first to the third
trimester. This is a highly regulated response to satisfy energy and membrane demands of …
trimester. This is a highly regulated response to satisfy energy and membrane demands of …
Lipidomic assessment of plasma and placenta of women with early-onset preeclampsia
Introduction Adipose tissue is responsible for triggering chronic systemic inflammatory
response and these changes may be involved in the pathophysiology of preeclampsia …
response and these changes may be involved in the pathophysiology of preeclampsia …
The maternal blood lipidome is indicative of the pathogenesis of severe preeclampsia
Preeclampsia is a pregnancy-specific syndrome characterized by hypertension and
proteinuria after 20 weeks of gestation. However, it is not well understood what lipids are …
proteinuria after 20 weeks of gestation. However, it is not well understood what lipids are …
Role of dyslipidemia in preeclampsia—A review of lipidomic analysis of blood, placenta, syncytiotrophoblast microvesicles and umbilical cord artery from women with …
D Wojcik-Baszko, K Charkiewicz… - Prostaglandins & Other …, 2018 - Elsevier
Preeclampsia is a complex disorder and the pathogenesis of it is still not fully understood.
The most commonly accepted theory of pathogenesis assumes that there occurs impaired …
The most commonly accepted theory of pathogenesis assumes that there occurs impaired …
Placental lipid metabolism in preeclampsia
AA Khaire, SR Thakar, GN Wagh… - Journal of …, 2021 - journals.lww.com
Objectives: The current study examines the placental and maternal lipid profile and
expression of genes involved in placental lipid metabolism in women with preeclampsia …
expression of genes involved in placental lipid metabolism in women with preeclampsia …
Maternal and fetal modulators of lipid metabolism correlate with the development of preeclampsia
JT Mural, E Muzykanskiy, RN Taylor - Metabolism, 1997 - Elsevier
The pregnancy syndrome preeclampsia is associated with placental dysfunction,
dyslipidemia, and endothelial cell activation, and is a major cause of maternal and fetal …
dyslipidemia, and endothelial cell activation, and is a major cause of maternal and fetal …
Is the atherosclerotic phenotype of preeclamptic placentas due to altered lipoprotein concentrations and placental lipoprotein receptors? Role of a small-for …
MR Hentschke, CE Poli-de-Figueiredo… - Journal of Lipid …, 2013 - ASBMB
Atherosis of spiral arteries in uteroplacental beds from preeclamptic women resemble those
of atherosclerosis, characterized by increased plasma lipids and lipoproteins. We …
of atherosclerosis, characterized by increased plasma lipids and lipoproteins. We …
Lipid fingerprinting in women with early-onset preeclampsia: a first look
OBJECTIVES: The aim of this preliminary study was to characterize the plasma lipid profiling
of women with preeclampsia. DESIGN AND METHODS: Plasma samples of 8 pregnant …
of women with preeclampsia. DESIGN AND METHODS: Plasma samples of 8 pregnant …
Effects of obesity and gestational diabetes mellitus on placental phospholipids
Gestational diabetes mellitus (GDM) is associated with adverse effects in the offspring. The
composition of placental glycerophospholipids (GPL) is known to be altered in GDM and …
composition of placental glycerophospholipids (GPL) is known to be altered in GDM and …