New therapeutic options for the treatment of patients with disorders of consciousness: the field of neuromodulation

A Thibaut, ND Schiff - Coma and Disorders of Consciousness, 2018 - Springer
Neuromodulation techniques aimed at normalizing the neurophysiologic disturbance
produced by brain lesions or dysfunction have been studied for years in attempts to …

Disorders of consciousness and electrophysiological treatment strategies: a review of the literature and new perspectives

A Guerra, E Maria Costantini, S Maatta… - Current …, 2014 - ingentaconnect.com
The last years have witnessed a significant increase in our understanding of brain functions
in survivors of severe brain injuries with disorders of consciousness (DOC). Despite there is …

Brain stimulation in patients with disorders of consciousness

A Thibaut, S Laureys - Principles and Practice of Clinical Research, 2015 - orbi.uliege.be
Background and Aim: There is a long history of brain stimulation in medical science, and it
was tested for years trying to treat several neurological diseases. On the other hand, the …

Deep brain stimulation

M Thonnard - Coma and disorders of consciousness, 2012 - Springer
Currently, disorders of consciousness are relatively well defined but therapeutic options
remain relatively restricted. Because empirical evidence for pharmacological treatments is …

Transcranial direct current stimulation in disorders of consciousness: a review

Y Zhang, W Song - International Journal of Neuroscience, 2018 - Taylor & Francis
It is a challenge to evaluate and treat the patients with disorders of consciousness (DOC) in
the clinic. Due to the huge costs of prolonged intensive care, the management of these …

Clinical neuromodulatory effects of deep brain stimulation in disorder of consciousness: A literature review

T Cao, S He, L Wang, X Chai, Q He… - CNS Neuroscience …, 2024 - Wiley Online Library
Background The management of patients with disorders of consciousness (DOC) presents
substantial challenges in clinical practice. Deep brain stimulation (DBS) has emerged as a …

Deep brain stimulation for disorders of consciousness: systematic review of cases and ethics

J Vanhoecke, M Hariz - Brain stimulation, 2017 - Elsevier
Background A treatment for patients suffering from prolonged severely altered
consciousness is not available. The success of Deep Brain Stimulation (DBS) in diseases …

Current status of neuromodulatory therapies for disorders of consciousness

X Xia, Y Yang, Y Guo, Y Bai, Y Dang, R Xu, J He - Neuroscience Bulletin, 2018 - Springer
Abstract Treatment for disorders of consciousness (DOCs) is still a Gordian knot. Evidence-
based guidelines on the treatment of DOC patients are not currently available, while …

Structural changes in brains of patients with disorders of consciousness treated with deep brain stimulation

M Raguž, N Predrijevac, D Dlaka, D Orešković… - Scientific reports, 2021 - nature.com
Disorders of consciousness (DOC) are one of the major consequences after anoxic or
traumatic brain injury. So far, several studies have described the regaining of consciousness …

Electromagnetic brain stimulation in patients with disorders of consciousness

P Bourdillon, B Hermann, JD Sitt… - Frontiers in …, 2019 - frontiersin.org
Severe brain injury is a common cause of coma. In some cases, despite vigilance
improvement, disorders of consciousness (DoC) persist. Several states of impaired …